Framework Overview

Workflow Summary
Overview of IOBRportal architecture, including data foundation, analysis workflows, and downstream visualization outputs.
IOBRportal at a glance

Explore modular tools and pre-defined workflows for end-to-end TME and immuno-oncology analyses. IOBRportal provides an integrated interface for transcriptome preprocessing, signature scoring, TME deconvolution, statistical analysis, and visualization.

The portal provides both function-oriented tools and workflow-oriented analysis routes, allowing users to start from individual tasks or follow guided pipelines for end-to-end interpretation in a unified and reproducible interface.

It is designed for both pre-integrated public cohorts and user-uploaded datasets. For dataset scale, cohort composition, and distribution statistics, please refer to Workflows → Datasets → Overview.

64362

Total Samples

396

Datasets

36

Cancer Types

4

Data Sections

Workflow-driven analysis
Move from data preparation to downstream statistics through guided pipelines.
Integrated cohort resources
Analyze pre-integrated public cohorts or your own uploaded expression/clinical datasets.
Output-ready visualizations
Generate interpretable plots for signatures, TME patterns, correlations, and survival outcomes.
Learning Resources
📖 Detailed Tutorial: https://qingcongl.github.io/IOBRportal_book/
💻 Code Repository: https://github.com/IOBR/IOBRportal
🌐 Web Portal: https://iobr.github.io/IOBRportal

Count2tpm : Converts raw gene counts to TPM.

Parameter

Data Download

Plot and Data

Anno_eset : Annotates an ExpressionSet with gene symbols.

Parameter

Data Download

Plot and Data

Remove_duplicate_genes : Aggregate duplicate gene symbols using Mean, SD, or Sum.

Parameter

Data Download

Result Data

Find_outlier_samples : Identify and remove outlier samples.

Parameter

Data Download

Plot and Data

Download Plot

You can manually adjust the width and height to resize the plot as needed.

Identified Outlier Samples: 

                                

                              

                            

                          

                          
                        

                      

                    

                    
                  

                

              

            

            

              
Remove_batcheffect
      :
       Integrate and correct batch effects from multiple datasets.

              

                

                  

                    

                      

                        
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                                          Download Plot
                                        
                                      

                                    

                                    

                                    
You can manually adjust the width and height to resize the plot as needed.

                                  

                                  

                                

                              

                            

                          

                          
                        

                      

                    

                    
                  

                

              

            

            

              
Mouse2human_eset
      :
       Convert mouse gene symbols in an expression set to human homologs.

              

                

                  

                    

                      

                        
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The parameter must be specified if 'Matrix' is FALSE.

                      

                    

                    
                  

                  

                    

                      

                        
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Result Data

                        

                          
                          
                        

                      

                      

                        

                          

                            

                              
                            

                            

                              

                                

                                  
                                  

                                

                              

                            

                          

                          
                        

                      

                    

                    
                  

                

              

            

            

              
Calculate_sig_score
      :
       Computes signature scores using PCA, ssGSEA, z-score, or integration.

              

                

                  

                    

                      

                        
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Deconvo_tme
      :
       Performs immune deconvolution using multiple algorithms.

              

                

                  

                    

                      

                        
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Note: CIBERSORT will take a long time.

                          

                            
                            
                          

                          

                            
                            

                              
                              
                            

                          

                          

                            
                            

                              
                              
                            

                          

                          

                            
                            

                              
                              
                            

                          

                          

                          
Note: Parallel can accelerate the calculation.

                        

                        

                          

                            
                            

                              
                              
                            

                          

                          

                            
                            

                              
                              
                            

                          

                        

                        

                          

                            
                            

                              
                              
                            

                          

                          

                            
                            

                              
                              
                            

                          

                          

                            
                            

                              
                              
                            

                          

                        

                        

                          

                            
                            

                              
                              
                            

                          

                        

                        

                          

                            
                            

                              
                              
                            

                          

                        

                        

                          

                            
                            

                              
                              
                            

                          

                        

                        

                          

                          
Note: This pipeline runs ALL algorithms and calculates signatures. It may take a while.

                          

                            
                            

                              
                              
                            

                          

                          

                            
                            
                          

                          

                            
                            

                              
                              
                            

                          

                        

                      

                    

                    
                  

                  

                    

                      

                        
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Tme_cluster
      :
       Performs tumor microenvironment clustering analysis.

              

                

                  

                    

                      

                        
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Optional: select interesting features for TME clustering; leave empty to skip this step.

                        

                          
                        

                        

                          
                          
                        

                        

                          
                          
                        

                        

                          
                          
                        

                      

                    

                    
                  

                  

                    

                      

                        
Data Download

                        

                          
                          
                        

                      

                      

                        

                          
                          

                            
                            
                          

                        

                        
                      

                    

                    
                  

                

                

                  

                    

                      

                        
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                                          Download Plot
                                        
                                      

                                    

                                    

                                    
You can manually adjust the width and height to resize the plot as needed.

                                  

                                  

                                

                                

                                  
                                  

                                

                                

                                  

                                

                              

                            

                          

                          
                        

                      

                    

                    
                  

                

              

            

            

              
LR_cal
      :
       Quantifies ligand-receptor interactions in the tumor microenvironment.

              

                

                  

                    

                      

                        
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Note: LR_cal will take a long time.

                      

                    

                    
                  

                  

                    

                      

                        
Data Download

                        

                          
                          
                        

                      

                      

                        

                          
                          

                            
                            
                          

                        

                        
                      

                    

                    
                  

                

                

                  

                    

                      

                        
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Batch_surv
      :
       Runs survival Cox analysis for multiple features.

              

                

                  

                    

                      

                        
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Data Download

                        

                          
                          
                        

                      

                      

                        

                          
                          

                            
                            
                          

                        

                        
                      

                    

                    
                  

                

                

                  

                    

                      

                        
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Batch_cor
      :
       Calculates Pearson or Spearman correlations across multiple feature pairs.

              

                

                  

                    

                      

                        
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Data Download

                        

                          
                          
                        

                      

                      

                        

                          
                          

                            
                            
                          

                        

                        
                      

                    

                    
                  

                

                

                  

                    

                      

                        
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Batch_pcc
      :
       Computes partial correlations while adjusting for a third variable.

              

                

                  

                    

                      

                        
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Data Download

                        

                          
                          
                        

                      

                      

                        

                          
                          

                            
                            
                          

                        

                        
                      

                    

                    
                  

                

                

                  

                    

                      

                        
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Batch_wilcoxon
      :
       Runs Wilcoxon rank-sum tests on multiple features (for two groups).

              

                

                  

                    

                      

                        
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Data Download

                        

                          
                          
                        

                      

                      

                        

                          
                          

                            
                            
                          

                        

                        
                      

                    

                    
                  

                

                

                  

                    

                      

                        
Plot and Data

                        

                          
                          
                        

                      

                      

                        

                          

                            

                              
                            

                            

                              

                                

                                  
                                  

                                

                              

                            

                          

                          
                        

                      

                    

                    
                  

                

              

            

            

              
batch_kruskal
      :
       Runs Kruskal–Wallis tests on multiple features (for three or more groups).

              

                

                  

                    

                      

                        
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Data Download

                        

                          
                          
                        

                      

                      

                        

                          
                          

                            
                            
                          

                        

                        
                      

                    

                    
                  

                

                

                  

                    

                      

                        
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Sig_heatmap
      :
       Draws customizable heatmaps grouped by annotations or conditions.

              

                

                  

                    

                      

                        
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Input hex codes or color names separated by comma. If filled, 'Palette Group' will be ignored.

                        

                          
                          
                        

                        

                        
Provide at least 3 colors separated by comma. Used for heatmap low-mid-high values.

                        

                          
                          
                        

                      

                    

                    
                  

                

                

                  

                    

                      

                        
Plot

                        

                          
                          
                        

                      

                      

                        

                          

                            

                              
                            

                            

                              

                                

                                  

                                    

                                      

                                        

                                          
                                          
                                        

                                      

                                      

                                        

                                          
                                          
                                        

                                      

                                      

                                        
                                          
                                          Download Plot
                                        
                                      

                                    

                                    

                                    
You can manually adjust the width and height to resize the plot as needed.

                                  

                                  

                                

                              

                            

                          

                          
                        

                      

                    

                    
                  

                

              

            

            

              
Sig_box
      :
       Creates customizable boxplots for signatures or variables.

              

                

                  

                    

                      

                        
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Input hex codes or color names separated by comma. If filled, 'Palette' will be ignored.

                        

                          
                          

                            
                            
                          

                        

                        

                          
                          

                            
                            
                          

                        

                        

                          
                          

                            
                            
                          

                        

                        

                          
                          
                        

                        

                          
                          
                        

                        

                          
                          
                        

                        

                          
                          
                        

                        

                          
                          
                        

                      

                    

                    
                  

                

                

                  

                    

                      

                        
Plot and Data

                        

                          
                          
                        

                      

                      

                        

                          

                            

                              
                            

                            

                              

                                

                                  

                                    

                                      

                                        

                                          
                                          
                                        

                                      

                                      

                                        

                                          
                                          
                                        

                                      

                                      

                                        
                                          
                                          Download Plot
                                        
                                      

                                    

                                    

                                    
You can manually adjust the width and height to resize the plot as needed.

                                  

                                  

                                

                              

                            

                          

                          
                        

                      

                    

                    
                  

                

              

            

            

              
Sig_surv_plot
      :
       Generates multiple KM survival curves for genes or signatures.

              

                

                  

                    

                      

                        
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Input hex codes or color names separated by comma. If filled, 'Palette' will be ignored.

                      

                    

                    
                  

                

                

                  

                    

                      

                        
Plot and Data

                        

                          
                          
                        

                      

                      

                        

                          

                            

                              
                            

                            

                              

                                

                                  

                                    

                                      

                                        

                                          
                                          
                                        

                                      

                                      

                                        

                                          
                                          
                                        

                                      

                                      

                                        
                                          
                                          Download Plot
                                        
                                      

                                    

                                    

                                    
You can manually adjust the width and height to resize the plot as needed.

                                  

                                  

                                

                              

                            

                          

                          
                        

                      

                    

                    
                  

                

              

            

            

              
Roc_time
      :
       Generates time-dependent ROC curves with AUC values.

              

                

                  

                    

                      

                        
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Input hex codes or color names separated by comma. If filled, 'Palette' will be ignored.

                        

                          
                          
                        

                      

                    

                    
                  

                

                

                  

                    

                      

                        
Plot and Data

                        

                          
                          
                        

                      

                      

                        

                          

                            

                              
                            

                            

                              

                                

                                  

                                    

                                      

                                        

                                          
                                          
                                        

                                      

                                      

                                        

                                          
                                          
                                        

                                      

                                      

                                        
                                          
                                          Download Plot
                                        
                                      

                                    

                                    

                                    
You can manually adjust the width and height to resize the plot as needed.

                                  

                                  

                                

                              

                            

                          

                          
                        

                      

                    

                    
                  

                

              

            

            

              
Sig_forest
      :
       Produces forest plots from batch survival results.

              

                

                  

                    

                      

                        
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Note: Supports data from Signature Data rather than TME data.

                        

                          
                          
                        

                        

                          
                          
                        

                        

                          
                          
                        

                        

                          
                          
                        

                        

                          
                          
                        

                        

                          
                          
                        

                        

                          
                          
                        

                        

                          
                          
                        

                        

                          
                          
                        

                        

                        
Input hex codes or color names separated by comma. If filled, 'Palette' will be ignored.

                      

                    

                    
                  

                

                

                  

                    

                      

                        
Plot and Data

                        

                          
                          
                        

                      

                      

                        

                          

                            

                              
                            

                            

                              

                                

                                  

                                    

                                      

                                        

                                          
                                          
                                        

                                      

                                      

                                        

                                          
                                          
                                        

                                      

                                      

                                        
                                          
                                          Download Plot
                                        
                                      

                                    

                                    

                                    
You can manually adjust the width and height to resize the plot as needed.

                                  

                                  

                                

                              

                            

                          

                          
                        

                      

                    

                    
                  

                

              

            

            

              
Get_cor
      :
       Computes and plots correlation between two variables with regression options.

              

                

                  

                    

                      

                        
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Input hex codes or color names separated by comma. If you have group like subtype.

                        

                          
                          
                        

                        

                          
                          
                        

                        

                          
                          
                        

                        

                          
                          
                        

                        

                          
                          
                        

                        

                          
                          
                        

                        

                          
                          
                        

                      

                    

                    
                  

                

                

                  

                    

                      

                        
Plot and Data

                        

                          
                          
                        

                      

                      

                        

                          

                            

                              
                            

                            

                              

                                

                                  

                                    

                                      

                                        

                                          
                                          
                                        

                                      

                                      

                                        

                                          
                                          
                                        

                                      

                                      

                                        
                                          
                                          Download Plot
                                        
                                      

                                    

                                    

                                    
You can manually adjust the width and height to resize the plot as needed.

                                  

                                  

                                

                              

                            

                          

                          
                        

                      

                    

                    
                  

                

              

            

            

              
Get_cor_matrix
      :
       Calculates and displays a correlation matrix for variable groups.

              

                

                  

                    

                      

                        
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Provide 2 or 3 colors separated by comma. 2 colors = low/high (mid=white); 3 colors = low/mid/high.

                        

                          
                          

                            
                            
                          

                        

                        

                          
                          

                            
                            
                          

                        

                        

                          
                          
                        

                        

                          
                          
                        

                        

                          
                          

                            
                            
                          

                        

                      

                    

                    
                  

                

                

                  

                    

                      

                        
Plot and Data

                        

                          
                          
                        

                      

                      

                        

                          

                            

                              
                            

                            

                              

                                

                                  

                                    

                                      

                                        

                                          
                                          
                                        

                                      

                                      

                                        

                                          
                                          
                                        

                                      

                                      

                                        
                                          
                                          Download Plot
                                        
                                      

                                    

                                    

                                    
You can manually adjust the width and height to resize the plot as needed.

                                  

                                  

                                

                              

                            

                          

                          
                        

                      

                    

                    
                  

                

              

            

            

              
IOBR_pca
      :
       Perform Principal Component Analysis (PCA).

              

                

                  

                    

                      

                        
Parameter

                        

                          
                          
                        

                      

                      

                        

                          

                            
                            

                              
                              
                            

                            

                              

                            

                          

                          

                            
                          

                        

                        

                          

                            
                            

                              
                              
                            

                            

                              

                            

                          

                          

                            
                          

                        

                        

                          
                        

                        

                          
                          
                        

                        

                          
                          
                        

                        

                          
                          

                            
                            
                          

                        

                        

                          
                          

                            
                            
                          

                        

                        

                          
                          

                            
                            
                          

                        

                        

                          
                          

                            
                            
                          

                        

                        

                          
                          

                            
                            
                          

                        

                        

                          
                          
                        

                        

                        
Input hex codes or color names separated by comma. If filled, 'Palette' will be ignored.

                        

                          
                          

                            
                            
                          

                        

                        

                          
                          
                        

                        

                          

                            

                              
                              

                                
                                
                              

                            

                          

                          

                            

                              
                              

                                
                                
                              

                            

                          

                        

                        

                          
                          

                            
                            
                          

                        

                      

                    

                    
                  

                

                

                  

                    

                      

                        
Plot Result

                        

                          
                          
                        

                      

                      

                        

                          

                            

                              
                            

                            

                              

                                

                                  

                                    

                                      

                                        

                                          
                                          
                                        

                                      

                                      

                                        

                                          
                                          
                                        

                                      

                                      

                                        
                                          
                                          Download Plot
                                        
                                      

                                    

                                    

                                    
You can manually adjust the width and height to resize the plot as needed.

                                  

                                  

                                

                              

                            

                          

                          
                        

                      

                    

                    
                  

                

              

            

            

              
Cell_bar_plot
      :
       Visualizes cell composition or immune infiltration profiles across samples.

              

                

                  

                    

                      

                        
Parameter

                        

                          
                          
                        

                      

                      

                        

                          

                            
                            

                              
                              
                            

                            

                              

                            

                          

                          

                            
                          

                        

                        

                          
                        

                        

                        

                          
                          
                        

                        

                          
                          
                        

                        

                        
Note: Supports data from deconvolution methods such as CIBERSORT, EPIC, and quanTIseq.

                        

                          
                          
                        

                        

                          
                          
                        

                        

                        
Input hex codes or color names separated by comma.

                        

                          
                          
                        

                        

                          
                          

                            
                            
                          

                        

                        

                          
                          

                            
                            
                          

                        

                        

                          
                          

                            
                            
                          

                        

                      

                    

                    
                  

                

                

                  

                    

                      

                        
Plot and Data

                        

                          
                          
                        

                      

                      

                        

                          

                            

                              
                            

                            

                              

                                

                                  

                                    

                                      

                                        

                                          
                                          
                                        

                                      

                                      

                                        

                                          
                                          
                                        

                                      

                                      

                                        
                                          
                                          Download Plot
                                        
                                      

                                    

                                    

                                    
You can manually adjust the width and height to resize the plot as needed.

                                  

                                  

                                

                              

                            

                          

                          
                        

                      

                    

                    
                  

                

              

            

            

              
Surv_group
      : 
      Generates Kaplan-Meier survival plots for categorical grouping variables.

              

                

                  

                    

                      

                        
Parameter

                        

                          
                          
                        

                      

                      

                        

                          

                            
                            

                              
                              
                            

                            

                              

                            

                          

                          

                            
                          

                        

                        

                          
                        

                        

                          
                          
                        

                        

                          
                          
                        

                        

                          
                          
                        

                        

                          
                          
                        

                        

                          
                          

                            
                            
                          

                        

                        

                          
                          

                            
                            
                          

                        

                        

                          
                          
                        

                        

                        
Input hex codes or color names separated by comma. If filled, 'Palette' will be ignored.

                        

                          
                          
                        

                      

                    

                    
                  

                

                

                  

                    

                      

                        
Plot and Data

                        

                          
                          
                        

                      

                      

                        

                          

                            

                              
                            

                            

                              

                                

                                  

                                    

                                      

                                        

                                          
                                          
                                        

                                      

                                      

                                        

                                          
                                          
                                        

                                      

                                      

                                        
                                          
                                          Download Plot
                                        
                                      

                                    

                                    

                                    
You can manually adjust the width and height to resize the plot as needed.

                                  

                                  

                                

                              

                            

                          

                          
                        

                      

                    

                    
                  

                

              

            

            

              
Sig_roc
      :
       Generates ROC curves for significant signatures.

              

                

                  

                    

                      

                        
Parameter

                        

                          
                          
                        

                      

                      

                        

                          

                            
                            

                              
                              
                            

                            

                              

                            

                          

                          

                            
                          

                        

                        

                          
                        

                        

                          
                          
                        

                        

                          
                          
                        

                        

                          
                          

                            
                            
                          

                        

                        

                          
                          
                        

                        

                        
Input hex codes or color names separated by comma. If filled, 'Palette' will be ignored.

                        

                          
                          
                        

                        

                          
                          

                            
                            
                          

                        

                        

                          

                            
                            

                              
                              
                            

                          

                        

                        

                          
                          

                            
                            
                          

                        

                        

                          
                          
                        

                      

                    

                    
                  

                

                

                  

                    

                      

                        
Plot and Data

                        

                          
                          
                        

                      

                      

                        

                          

                            

                              
                            

                            

                              

                                

                                  

                                    

                                      

                                        

                                          
                                          
                                        

                                      

                                      

                                        

                                          
                                          
                                        

                                      

                                      

                                        
                                          
                                          Download Plot
                                        
                                      

                                    

                                    

                                    
You can manually adjust the width and height to resize the plot as needed.

                                  

                                  

                                

                              

                            

                          

                          
                        

                      

                    

                    
                  

                

              

            

            

              
Percent_bar_plot
      :
       Plots percentage bar charts for categorical variables.

              

                

                  

                    

                      

                        
Parameter

                        

                          
                          
                        

                      

                      

                        

                          

                            
                            

                              
                              
                            

                            

                              

                            

                          

                          

                            
                          

                        

                        

                          
                        

                        

                        

                          
                          
                        

                        

                          
                          
                        

                        

                          
                          

                            
                            
                          

                        

                        

                          
                          
                        

                        

                        
Input hex codes or color names separated by comma. If filled, 'Palette' will be ignored.

                        

                          
                          
                        

                        

                          
                          
                        

                        

                          
                          

                            
                            
                          

                        

                        

                          
                          

                            
                            
                          

                        

                        

                          
                          
                        

                        

                          
                          
                        

                        

                          
                          

                            
                            
                          

                        

                      

                    

                    
                  

                

                

                  

                    

                      

                        
Plot and Data

                        

                          
                          
                        

                      

                      

                        

                          

                            

                              
                            

                            

                              

                                

                                  

                                    

                                      

                                        

                                          
                                          
                                        

                                      

                                      

                                        

                                          
                                          
                                        

                                      

                                      

                                        
                                          
                                          Download Plot
                                        
                                      

                                    

                                    

                                    
You can manually adjust the width and height to resize the plot as needed.

                                  

                                  

                                

                              

                            

                          

                          
                        

                      

                    

                    
                  

                

              

            

            

              
Sig_gsea
      :
        Performs GSEA analysis based on differential expression results.

              

                

                  

                    

                      

                        
Parameter for data

                        

                          
                          
                        

                      

                      

                        

                          

                            
                            

                              
                              
                            

                            

                              

                            

                          

                          

                            
                          

                        

                        

                          

                            
                            

                              
                              
                            

                            

                              

                            

                          

                          

                            
                          

                        

                        

                          
                        

                        

                          
                          
                        

                        

                          
                          
                        

                        
                        

                          

                            

                              
                              
                            

                          

                          

                            

                              
                              
                            

                          

                        

                        

                          
                          

                            
                            
                          

                        

                        

                          
                          

                            
                            
                          

                        

                        

                        
DESeq2 uses raw counts and Limma uses log2-transformed TPM values.

                        

                          
                          
                        

                        

                          
                          
                        

                      

                    

                    
                  

                  

                    

                      

                        
Parameter for plot

                        

                          
                          
                        

                      

                      

                        

                          
                        

                        

                          
                          

                            
                            
                          

                        

                        

                          
                          
                        

                        

                        
Input hex codes or color names separated by comma.

                        

                          
                          

                            
                            
                          

                        

                        

                          
                          
                        

                      

                    

                    
                  

                  

                    

                      

                        
Data Download

                        

                          
                          
                        

                      

                      

                        

                          
                          

                            
                            
                          

                        

                        
                      

                    

                    
                  

                

                

                  

                    

                      

                        
Plot and Data

                        

                          
                          
                        

                      

                      

                        

                          

                            

                              
                            

                            

                              

                                

                                  

                                    

                                      

                                        

                                          
                                          
                                        

                                      

                                      

                                        

                                          
                                          
                                        

                                      

                                      

                                        
                                          
                                          Download Plot
                                        
                                      

                                    

                                    

                                    
You can manually adjust the width and height to resize the plot as needed.

                                  

                                  

                                

                                

                                  
                                  

                                

                              

                            

                          

                          
                        

                      

                    

                    
                  

                

              

            

            

              
Find_markers_in_bulk
      :
      Identifies marker genes for each group using Seurat workflow on bulk data.

              

                

                  

                    

                      

                        
Parameter for data

                        

                          
                          
                        

                      

                      

                        

                          

                            
                            

                              
                              
                            

                            

                              

                            

                          

                          

                            
                          

                        

                        

                          

                            
                            

                              
                              
                            

                            

                              

                            

                          

                          

                            
                          

                        

                        

                          
                        

                        

                          
                          
                        

                        

                          
                          
                        

                        

                          
                          
                        

                        

                          
                          

                            
                            
                          

                        

                        

                          
                          

                            
                            
                          

                        

                        

                          
                          
                        

                        

                        
Input hex codes or color names separated by comma. If filled, 'Group Color' will be ignored.

                        

                          
                          
                        

                        

                        
Input hex codes or color names separated by comma. If filled, 'Heatmap Color' will be ignored.

                      

                    

                    
                  

                  

                    

                      

                        
Data Download

                        

                          
                          
                        

                      

                      

                        

                          
                          

                            
                            
                          

                        

                        
                      

                    

                    
                  

                

                

                  

                    

                      

                        
Plot and Data

                        

                          
                          
                        

                      

                      

                        

                          

                            

                              
                            

                            

                              

                                

                                  

                                    

                                      

                                        

                                          
                                          
                                        

                                      

                                      

                                        

                                          
                                          
                                        

                                      

                                      

                                        
                                          
                                          Download Plot
                                        
                                      

                                    

                                    

                                    
You can manually adjust the width and height to resize the plot as needed.

                                  

                                  

                                

                                

                                  
                                  

                                

                              

                            

                          

                          
                        

                      

                    

                    
                  

                

              

            

            

              
Make_mut_matrix
      :
       Converts MAF mutation data into a binary mutation matrix.

              

                

                  

                    

                      

                        
Parameter

                        

                          
                          
                        

                      

                      

                        

                          

                            
                            

                              
                              
                            

                            

                              

                            

                          

                          

                            
                          

                        

                        

                          
                        

                        

                          
                          

                            
                            
                          

                        

                        

                          
                          

                            
                            
                          

                        

                      

                    

                    
                  

                  

                    

                      

                        
Data Download

                        

                          
                          
                        

                      

                      

                        

                          
                          

                            
                            
                          

                        

                        
                      

                    

                    
                  

                

                

                  

                    

                      

                        
Plot and Data

                        

                          
                          
                        

                      

                      

                        

                          

                            

                              
                            

                            

                              

                                

                                  
                                  

                                

                              

                            

                          

                          
                        

                      

                    

                    
                  

                

              

            

            

              
Find_mutations
      :
       Identifies phenotype-associated mutations.

              

                

                  

                    

                      

                        
Parameter

                        

                          
                          
                        

                      

                      

                        

                          

                            
                            

                              
                              
                            

                            

                              

                            

                          

                          

                            
                          

                        

                        

                          

                            
                            

                              
                              
                            

                            

                              

                            

                          

                          

                            
                          

                        

                        
Note: Signature scores can be calculated using the IOBR Workflow then uploaded here.

                        

                          
                        

                        

                          
                          
                        

                        

                          
                          
                        

                        

                          
                          

                            
                            
                          

                        

                        

                          
                          

                            
                            
                          

                        

                      

                    

                    
                  

                  

                    

                      

                        
Parameter for oncoprint

                        

                          
                          
                        

                      

                      

                        

                          
                          

                            
                            
                          

                        

                        

                          
                          
                        

                        
Input a hex code or color name for mutation events.

                        

                          
                          
                        

                      

                    

                    
                  

                  

                    

                      

                        
Parameter for box plot

                        

                          
                          
                        

                      

                      

                        

                          
                          
                        

                        

                          
                          
                        

                        

                          
                          

                            
                            
                          

                        

                        

                          
                          
                        

                        

                        
Input hex codes or color names separated by comma. If filled, 'Palette' will be ignored.

                        

                          
                          

                            
                            
                          

                        

                      

                    

                    
                  

                  

                    

                      

                        
All Results Download

                        

                          
                          
                        

                      

                      

                        

                          
                          
                        

                        
                      

                    

                    
                  

                

                

                  

                    

                      

                        
Plot and Data

                        

                          
                          
                        

                      

                      

                        

                          

                            

                              
                            

                            

                              

                                

                                  

                                    

                                      

                                        

                                          
                                          
                                        

                                      

                                      

                                        

                                          
                                          
                                        

                                      

                                      

                                        
                                          
                                          Download Plot
                                        
                                      

                                    

                                    

                                    
You can manually adjust the width and height to resize the plot as needed.

                                  

                                  

                                

                                

                                  

                                    

                                      

                                        

                                          
                                          
                                        

                                      

                                      

                                        

                                          
                                          
                                        

                                      

                                      

                                        
                                          
                                          Download Plot
                                        
                                      

                                    

                                    

                                    
You can manually adjust the width and height to resize the plot as needed.

                                  

                                  

                                

                              

                            

                          

                          
                        

                      

                    

                    
                  

                

              

            

            

              

                
Mutation Workflow
      :
       Mutation Matrix Construction, Mutation–Signature Analysis, and Survival Analysis.

                

                  
                

              

              

                
                

                  

                    

                      

                        

                          

                            

                              
Parameter

                              

                                
                                
                              

                            

                            

                              

                                

                                  
                                  

                                    
                                    
                                  

                                  

                                    

                                  

                                

                                

                                  
                                

                              

                              

                                
                              

                              

                                
                                

                                  
                                  
                                

                              

                              

                                
                                

                                  
                                  
                                

                              

                            

                          

                          
                        

                        

                          

                            

                              
Data Download

                              

                                
                                
                              

                            

                            

                              

                                
                                

                                  
                                  
                                

                              

                              
                            

                          

                          
                        

                      

                      

                        

                          

                            

                              
Plot and Data

                              

                                
                                
                              

                            

                            

                              

                                

                                  

                                    
                                  

                                  

                                    

                                      

                                        
                                        

                                      

                                    

                                  

                                

                                
                              

                            

                          

                          
                        

                      

                    

                  

                  

                    

                      

                        

                          

                            

                              
Parameter

                              

                                
                                
                              

                            

                            

                              

                                

                                  
                                  

                                    
                                    
                                  

                                  

                                    

                                  

                                

                                

                                  
                                

                              

                              
Note: Signature scores can be calculated using the IOBR Workflow then uploaded here.

                              

                                
                              

                              

                                
                                
                              

                              

                                
                                
                              

                              

                                
                                

                                  
                                  
                                

                              

                              

                                
                                

                                  
                                  
                                

                              

                            

                          

                          
                        

                        

                          

                            

                              
Parameter for oncoprint

                              

                                
                                
                              

                            

                            

                              

                                
                                

                                  
                                  
                                

                              

                              

                                
                                
                              

                              
Input a hex code or color name for mutation events.

                              

                                
                                
                              

                            

                          

                          
                        

                        

                          

                            

                              
Parameter for box plot

                              

                                
                                
                              

                            

                            

                              

                                
                                
                              

                              

                                
                                
                              

                              

                                
                                

                                  
                                  
                                

                              

                              

                                
                                
                              

                              

                              
Input hex codes or color names separated by comma. If filled, 'Palette' will be ignored.

                              

                                
                                

                                  
                                  
                                

                              

                            

                          

                          
                        

                        

                          

                            

                              
All Results Download

                              

                                
                                
                              

                            

                            

                              

                                
                                
                              

                              
                            

                          

                          
                        

                      

                      

                        

                          

                            

                              
Plot and Data

                              

                                
                                
                              

                            

                            

                              

                                

                                  

                                    
                                  

                                  

                                    

                                      

                                        

                                          

                                            

                                              

                                                
                                                
                                              

                                            

                                            

                                              

                                                
                                                
                                              

                                            

                                            

                                              
                                                
                                                Download Plot
                                              
                                            

                                          

                                          

                                          
You can manually adjust the width and height to resize the plot as needed.

                                        

                                        

                                      

                                      

                                        

                                          

                                            

                                              

                                                
                                                
                                              

                                            

                                            

                                              

                                                
                                                
                                              

                                            

                                            

                                              
                                                
                                                Download Plot
                                              
                                            

                                          

                                          

                                          
You can manually adjust the width and height to resize the plot as needed.

                                        

                                        

                                      

                                    

                                  

                                

                                
                              

                            

                          

                          
                        

                      

                    

                  

                  

                    

                      
                      

                        

                          

                            

                              

                                

                                  

                                    
Parameter

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      

                                        
                                        

                                          
                                          
                                        

                                        

                                          

                                        

                                      

                                      

                                        
                                      

                                    

                                    

                                      
                                    

                                  

                                

                                
                              

                              

                                

                                  

                                    
Data Download

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    
                                  

                                

                                
                              

                            

                            

                              

                                

                                  

                                    
Plot and Data

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      

                                        

                                          
                                        

                                        

                                          

                                            

                                              
                                              

                                            

                                          

                                        

                                      

                                      
                                    

                                  

                                

                                
                              

                            

                          

                        

                        

                          

                            

                              

                                

                                  

                                    
Parameter

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                  

                                

                                
                              

                              

                                

                                  

                                    
Data Download

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    
                                  

                                

                                
                              

                            

                            

                              

                                

                                  

                                    
Plot and Data

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      

                                        

                                          
                                        

                                        

                                          

                                            

                                              
                                              

                                            

                                          

                                        

                                      

                                      
                                    

                                  

                                

                                
                              

                            

                          

                        

                        

                          

                            

                              

                                

                                  

                                    
Parameter

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      
                                    

                                    

                                    
Input hex codes or color names separated by comma. If filled, 'Palette' will be ignored.

                                    

                                      
                                      
                                    

                                  

                                

                                
                              

                            

                            

                              

                                

                                  

                                    
Plot and Data

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      

                                        

                                          
                                        

                                        

                                          

                                            

                                              

                                                

                                                  

                                                    

                                                      
                                                      
                                                    

                                                  

                                                  

                                                    

                                                      
                                                      
                                                    

                                                  

                                                  

                                                    
                                                      
                                                      Download Plot
                                                    
                                                  

                                                

                                                

                                                
You can manually adjust the width and height to resize the plot as needed.

                                              

                                              

                                            

                                          

                                        

                                      

                                      
                                    

                                  

                                

                                
                              

                            

                          

                        

                      

                    

                  

                

              

            

            

              

                
IOBR Workflow
      :
       Integrated Pipeline for Signature Scoring, TME Deconvolution, and Downstream Analysis.

                

                  
                

              

              

                
                

                  

                    

                    

                      
                      

                        

                          

                            

                              
                              

                                

                                  

                                    
                                  

                                  

                                    
                                  

                                

                              

                            

                            Note: Select Counts to TPM or Annotate ExpressionSet.
                          

                          

                            

                              

                                

                                  

                                    

                                      
Parameter

                                      

                                        
                                        
                                      

                                    

                                    

                                      

                                        

                                          
                                          

                                            
                                            
                                          

                                          

                                            

                                          

                                        

                                        

                                          
                                        

                                      

                                      

                                        
                                      

                                      

                                        
                                        

                                          
                                          
                                        

                                      

                                      

                                        

                                          
                                          

                                            
                                            
                                          

                                        

                                      

                                      

                                        

                                          
                                          

                                            
                                            
                                          

                                        

                                      

                                      

                                        
                                        

                                          
                                          
                                        

                                      

                                      

                                        
                                        

                                          
                                          
                                        

                                      

                                    

                                  

                                  
                                

                                

                                  

                                    

                                      
Data Download

                                      

                                        
                                        
                                      

                                    

                                    

                                      

                                        
                                        

                                          
                                          
                                        

                                      

                                      
                                    

                                  

                                  
                                

                              

                              

                                

                                  

                                    

                                      
Plot and Data

                                      

                                        
                                        
                                      

                                    

                                    

                                      

                                        

                                          

                                            
                                          

                                          

                                            

                                              

                                                
                                                

                                              

                                            

                                          

                                        

                                        
                                      

                                    

                                  

                                  
                                

                              

                            

                          

                          

                            

                              

                                

                                  

                                    

                                      
Parameter

                                      

                                        
                                        
                                      

                                    

                                    

                                      

                                        

                                          
                                          

                                            
                                            
                                          

                                          

                                            

                                          

                                        

                                        

                                          
                                        

                                      

                                      

                                        
                                      

                                      

                                        
                                        

                                          
                                          
                                        

                                      

                                      

                                        
                                        

                                          
                                          
                                        

                                      

                                      

                                        
                                        

                                          
                                          
                                        

                                      

                                    

                                  

                                  
                                

                                

                                  

                                    

                                      
Data Download

                                      

                                        
                                        
                                      

                                    

                                    

                                      

                                        
                                        

                                          
                                          
                                        

                                      

                                      
                                    

                                  

                                  
                                

                              

                              

                                

                                  

                                    

                                      
Plot and Data

                                      

                                        
                                        
                                      

                                    

                                    

                                      

                                        

                                          

                                            
                                          

                                          

                                            

                                              

                                                
                                                

                                              

                                            

                                          

                                        

                                        
                                      

                                    

                                  

                                  
                                

                              

                            

                          

                        

                        

                          

                            

                              

                                

                                  

                                    
Parameter

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      

                                        
                                      

                                    

                                    
Note: It is optional and defaults to True.

                                    

                                      
                                    

                                  

                                

                                
                              

                              

                                

                                  

                                    
Data Download

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    
                                  

                                

                                
                              

                            

                            

                              

                                

                                  

                                    
Plot and Data

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      

                                        

                                          
                                        

                                        

                                          

                                            

                                              
                                              

                                            

                                            

                                              

                                                

                                                  

                                                    

                                                      
                                                      
                                                    

                                                  

                                                  

                                                    

                                                      
                                                      
                                                    

                                                  

                                                  

                                                    
                                                      
                                                      Download Plot
                                                    
                                                  

                                                

                                                

                                                
You can manually adjust the width and height to resize the plot as needed.

                                              

                                              

                                            

                                            

                                              Identified Outlier Samples:
                                              

                                            

                                          

                                        

                                      

                                      
                                    

                                  

                                

                                
                              

                            

                          

                        

                        

                          

                            

                              
                              

                                

                                  

                                    
                                  

                                  

                                    
                                  

                                

                              

                            

                            Note: Select Calculate Sigscores or Deconvolute TME.
                          

                          

                            

                              

                                

                                  

                                    

                                      
Parameter

                                      

                                        
                                        
                                      

                                    

                                    

                                      

                                        
                                      

                                      

                                        
                                        

                                          
                                          
                                        

                                      

                                      

                                        
                                        

                                          
                                          
                                        

                                      

                                      

                                        
                                        
                                      

                                      

                                        
                                        

                                          
                                          
                                        

                                      

                                    

                                  

                                  
                                

                                

                                  

                                    

                                      
Data Download

                                      

                                        
                                        
                                      

                                    

                                    

                                      

                                        
                                        

                                          
                                          
                                        

                                      

                                      
                                    

                                  

                                  
                                

                              

                              

                                

                                  

                                    

                                      
Plot and Data

                                      

                                        
                                        
                                      

                                    

                                    

                                      

                                        

                                          

                                            
                                          

                                          

                                            

                                              

                                                
                                                

                                              

                                            

                                          

                                        

                                        
                                      

                                    

                                  

                                  
                                

                              

                            

                          

                          

                            

                              

                                

                                  

                                    

                                      
Parameter

                                      

                                        
                                        
                                      

                                    

                                    

                                      

                                        
                                      

                                      

                                        
                                        

                                          
                                          
                                        

                                      

                                      

                                        

                                          
                                          

                                            
                                            
                                          

                                        

                                        

                                        
Note: CIBERSORT will take a long time.

                                        

                                          
                                          
                                        

                                        

                                          
                                          

                                            
                                            
                                          

                                        

                                        

                                          
                                          

                                            
                                            
                                          

                                        

                                        

                                          
                                          

                                            
                                            
                                          

                                        

                                        

                                        
Note: Parallel can accelerate the calculation.

                                      

                                      

                                        

                                          
                                          

                                            
                                            
                                          

                                        

                                        

                                          
                                          

                                            
                                            
                                          

                                        

                                      

                                      

                                        

                                          
                                          

                                            
                                            
                                          

                                        

                                        

                                          
                                          

                                            
                                            
                                          

                                        

                                        

                                          
                                          

                                            
                                            
                                          

                                        

                                      

                                      

                                        

                                          
                                          

                                            
                                            
                                          

                                        

                                      

                                      

                                        

                                          
                                          

                                            
                                            
                                          

                                        

                                      

                                      

                                        

                                          
                                          

                                            
                                            
                                          

                                        

                                      

                                      

                                        

                                        
Note: This pipeline runs ALL algorithms and calculates signatures. It may take a while.

                                        

                                          
                                          

                                            
                                            
                                          

                                        

                                        

                                          
                                          
                                        

                                        

                                          
                                          

                                            
                                            
                                          

                                        

                                      

                                    

                                  

                                  
                                

                                

                                  

                                    

                                      
Data Download

                                      

                                        
                                        
                                      

                                    

                                    

                                      

                                        
                                        

                                          
                                          
                                        

                                      

                                      
                                    

                                  

                                  
                                

                              

                              

                                

                                  

                                    

                                      
Plot and Data

                                      

                                        
                                        
                                      

                                    

                                    

                                      

                                        

                                          

                                            
                                          

                                          

                                            

                                              

                                                
                                                

                                              

                                            

                                          

                                        

                                        
                                      

                                    

                                  

                                  
                                

                              

                            

                          

                        

                        

                          

                            

                              

                                

                                  

                                    
Parameter

                                    

                                      
                                      
                                    

                                  

                                  

                                    
Optional: select interesting features for TME clustering; leave empty to skip this step.

                                    

                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                  

                                

                                
                              

                              

                                

                                  

                                    
Data Download

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    
                                  

                                

                                
                              

                            

                            

                              

                                

                                  

                                    
Plot and Data

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      

                                        

                                          
                                        

                                        

                                          

                                            

                                              
                                              

                                            

                                            

                                              

                                            

                                          

                                        

                                      

                                      
                                    

                                  

                                

                                
                              

                            

                          

                        

                        

                          

                            

                              

                                

                                  

                                    
Parameter

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      

                                        
                                        

                                          
                                          
                                        

                                        

                                          

                                        

                                      

                                      

                                        
                                      

                                    

                                    

                                      
                                    

                                  

                                

                                
                              

                              

                                

                                  

                                    
Data Download

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    
                                  

                                

                                
                              

                            

                            

                              

                                

                                  

                                    
Combined Data Preview

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      

                                        

                                          
                                        

                                        

                                          

                                            

                                              
                                              

                                            

                                          

                                        

                                      

                                      
                                    

                                  

                                

                                
                              

                            

                          

                        

                      

                    

                  

                  

                    

                    

                      
                      

                        

                          

                            

                              

                                

                                  

                                    
Parameter

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      
                                    

                                    

                                    
Input hex codes or color names separated by comma. If filled, 'Palette Group' will be ignored.

                                    

                                      
                                      
                                    

                                    

                                    
Provide at least 3 colors separated by comma. Used for heatmap low-mid-high values.

                                    

                                      
                                      
                                    

                                  

                                

                                
                              

                            

                            

                              

                                

                                  

                                    
Plot

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      

                                        

                                          
                                        

                                        

                                          

                                            

                                              

                                                

                                                  

                                                    

                                                      
                                                      
                                                    

                                                  

                                                  

                                                    

                                                      
                                                      
                                                    

                                                  

                                                  

                                                    
                                                      
                                                      Download Plot
                                                    
                                                  

                                                

                                                

                                                
You can manually adjust the width and height to resize the plot as needed.

                                              

                                              

                                            

                                          

                                        

                                      

                                      
                                    

                                  

                                

                                
                              

                            

                          

                        

                        

                          

                            

                              

                                

                                  

                                    
Parameter

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      
                                    

                                    

                                    
Input hex codes or color names separated by comma. If filled, 'Palette' will be ignored.

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                  

                                

                                
                              

                            

                            

                              

                                

                                  

                                    
Plot and Data

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      

                                        

                                          
                                        

                                        

                                          

                                            

                                              

                                                

                                                  

                                                    

                                                      
                                                      
                                                    

                                                  

                                                  

                                                    

                                                      
                                                      
                                                    

                                                  

                                                  

                                                    
                                                      
                                                      Download Plot
                                                    
                                                  

                                                

                                                

                                                
You can manually adjust the width and height to resize the plot as needed.

                                              

                                              

                                            

                                          

                                        

                                      

                                      
                                    

                                  

                                

                                
                              

                            

                          

                        

                        

                          

                            

                              

                                

                                  

                                    
Parameter

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      
                                    

                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      
                                    

                                    

                                    
Input hex codes or color names separated by comma. If filled, 'Palette' will be ignored.

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                  

                                

                                
                              

                            

                            

                              

                                

                                  

                                    
Plot and Data

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      

                                        

                                          
                                        

                                        

                                          

                                            

                                              

                                                

                                                  

                                                    

                                                      
                                                      
                                                    

                                                  

                                                  

                                                    

                                                      
                                                      
                                                    

                                                  

                                                  

                                                    
                                                      
                                                      Download Plot
                                                    
                                                  

                                                

                                                

                                                
You can manually adjust the width and height to resize the plot as needed.

                                              

                                              

                                            

                                          

                                        

                                      

                                      
                                    

                                  

                                

                                
                              

                            

                          

                        

                        

                          

                            

                              

                                

                                  

                                    
Parameter

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      
                                    

                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                    
Note: Supports data from deconvolution methods such as CIBERSORT, EPIC, and quanTIseq.

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                    
Input hex codes or color names separated by comma.

                                    

                                      
                                      
                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                  

                                

                                
                              

                            

                            

                              

                                

                                  

                                    
Plot and Data

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      

                                        

                                          
                                        

                                        

                                          

                                            

                                              

                                                

                                                  

                                                    

                                                      
                                                      
                                                    

                                                  

                                                  

                                                    

                                                      
                                                      
                                                    

                                                  

                                                  

                                                    
                                                      
                                                      Download Plot
                                                    
                                                  

                                                

                                                

                                                
You can manually adjust the width and height to resize the plot as needed.

                                              

                                              

                                            

                                          

                                        

                                      

                                      
                                    

                                  

                                

                                
                              

                            

                          

                        

                      

                    

                  

                  

                    

                    

                      
                      

                        

                          

                            

                              

                                

                                  

                                    
Parameter

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                  

                                

                                
                              

                              

                                

                                  

                                    
Data Download

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    
                                  

                                

                                
                              

                            

                            

                              

                                

                                  

                                    
Plot and Data

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      

                                        

                                          
                                        

                                        

                                          

                                            

                                              
                                              

                                            

                                          

                                        

                                      

                                      
                                    

                                  

                                

                                
                              

                            

                          

                        

                        

                          

                            

                              

                                

                                  

                                    
Parameter

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                  

                                

                                
                              

                              

                                

                                  

                                    
Data Download

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    
                                  

                                

                                
                              

                            

                            

                              

                                

                                  

                                    
Plot and Data

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      

                                        

                                          
                                        

                                        

                                          

                                            

                                              
                                              

                                            

                                          

                                        

                                      

                                      
                                    

                                  

                                

                                
                              

                            

                          

                        

                        

                          

                            

                              

                                

                                  

                                    
Parameter

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                    
The signatures will be auto-selected

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      
                                    

                                    

                                    
Input hex codes or color names separated by comma. If filled, 'Palette Group' will be ignored.

                                    

                                      
                                      
                                    

                                    

                                    
Provide at least 3 colors separated by comma. Used for heatmap low-mid-high values.

                                    

                                      
                                      
                                    

                                  

                                

                                
                              

                            

                            

                              

                                

                                  

                                    
Plot

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      

                                        

                                          
                                        

                                        

                                          

                                            

                                              

                                                

                                                  

                                                    

                                                      
                                                      
                                                    

                                                  

                                                  

                                                    

                                                      
                                                      
                                                    

                                                  

                                                  

                                                    
                                                      
                                                      Download Plot
                                                    
                                                  

                                                

                                                

                                                
You can manually adjust the width and height to resize the plot as needed.

                                              

                                              

                                            

                                          

                                        

                                      

                                      
                                    

                                  

                                

                                
                              

                            

                          

                        

                        

                          

                            

                              

                                

                                  

                                    
Parameter

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      
                                    

                                    

                                    
Input hex codes or color names separated by comma. If filled, 'Palette' will be ignored.

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                  

                                

                                
                              

                            

                            

                              

                                

                                  

                                    
Plot and Data

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      

                                        

                                          
                                        

                                        

                                          

                                            

                                              

                                                

                                                  

                                                    

                                                      
                                                      
                                                    

                                                  

                                                  

                                                    

                                                      
                                                      
                                                    

                                                  

                                                  

                                                    
                                                      
                                                      Download Plot
                                                    
                                                  

                                                

                                                

                                                
You can manually adjust the width and height to resize the plot as needed.

                                              

                                              

                                            

                                          

                                        

                                      

                                      
                                    

                                  

                                

                                
                              

                            

                          

                        

                      

                    

                  

                  

                    

                    

                      
                      

                        

                          

                            

                              

                                

                                  

                                    
Parameter

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                  

                                

                                
                              

                              

                                

                                  

                                    
Data Download

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    
                                  

                                

                                
                              

                            

                            

                              

                                

                                  

                                    
Plot and Data

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      

                                        

                                          
                                        

                                        

                                          

                                            

                                              
                                              

                                            

                                          

                                        

                                      

                                      
                                    

                                  

                                

                                
                              

                            

                          

                        

                        

                          

                            

                              

                                

                                  

                                    
Parameter

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      
                                    

                                    

                                    
Note: Supports data from Signature Data rather than TME data.

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                    
Input hex codes or color names separated by comma. If filled, 'Palette' will be ignored.

                                  

                                

                                
                              

                            

                            

                              

                                

                                  

                                    
Plot and Data

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      

                                        

                                          
                                        

                                        

                                          

                                            

                                              

                                                

                                                  

                                                    

                                                      
                                                      
                                                    

                                                  

                                                  

                                                    

                                                      
                                                      
                                                    

                                                  

                                                  

                                                    
                                                      
                                                      Download Plot
                                                    
                                                  

                                                

                                                

                                                
You can manually adjust the width and height to resize the plot as needed.

                                              

                                              

                                            

                                          

                                        

                                      

                                      
                                    

                                  

                                

                                
                              

                            

                          

                        

                        

                          

                            

                              

                                

                                  

                                    
Parameter

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                    
The signatures will be auto-selected

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      
                                    

                                    

                                    
Input hex codes or color names separated by comma. If filled, 'Palette Group' will be ignored.

                                    

                                      
                                      
                                    

                                    

                                    
Provide at least 3 colors separated by comma. Used for heatmap low-mid-high values.

                                    

                                      
                                      
                                    

                                  

                                

                                
                              

                            

                            

                              

                                

                                  

                                    
Plot

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      

                                        

                                          
                                        

                                        

                                          

                                            

                                              

                                                

                                                  

                                                    

                                                      
                                                      
                                                    

                                                  

                                                  

                                                    

                                                      
                                                      
                                                    

                                                  

                                                  

                                                    
                                                      
                                                      Download Plot
                                                    
                                                  

                                                

                                                

                                                
You can manually adjust the width and height to resize the plot as needed.

                                              

                                              

                                            

                                          

                                        

                                      

                                      
                                    

                                  

                                

                                
                              

                            

                          

                        

                        

                          

                            

                              

                                

                                  

                                    
Parameter

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      
                                    

                                    

                                    
Input hex codes or color names separated by comma. If filled, 'Palette' will be ignored.

                                  

                                

                                
                              

                            

                            

                              

                                

                                  

                                    
Plot and Data

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      

                                        

                                          
                                        

                                        

                                          

                                            

                                              

                                                

                                                  

                                                    

                                                      
                                                      
                                                    

                                                  

                                                  

                                                    

                                                      
                                                      
                                                    

                                                  

                                                  

                                                    
                                                      
                                                      Download Plot
                                                    
                                                  

                                                

                                                

                                                
You can manually adjust the width and height to resize the plot as needed.

                                              

                                              

                                            

                                          

                                        

                                      

                                      
                                    

                                  

                                

                                
                              

                            

                          

                        

                        

                          

                            

                              

                                

                                  

                                    
Parameter

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      
                                    

                                    

                                    
Input hex codes or color names separated by comma. If filled, 'Palette' will be ignored.

                                    

                                      
                                      
                                    

                                  

                                

                                
                              

                            

                            

                              

                                

                                  

                                    
Plot and Data

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      

                                        

                                          
                                        

                                        

                                          

                                            

                                              

                                                

                                                  

                                                    

                                                      
                                                      
                                                    

                                                  

                                                  

                                                    

                                                      
                                                      
                                                    

                                                  

                                                  

                                                    
                                                      
                                                      Download Plot
                                                    
                                                  

                                                

                                                

                                                
You can manually adjust the width and height to resize the plot as needed.

                                              

                                              

                                            

                                          

                                        

                                      

                                      
                                    

                                  

                                

                                
                              

                            

                          

                        

                        

                          

                            

                              

                                

                                  

                                    
Parameter

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      
                                    

                                    

                                    
Input hex codes or color names separated by comma. If filled, 'Palette' will be ignored.

                                    

                                      
                                      
                                    

                                  

                                

                                
                              

                            

                            

                              

                                

                                  

                                    
Plot and Data

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      

                                        

                                          
                                        

                                        

                                          

                                            

                                              

                                                

                                                  

                                                    

                                                      
                                                      
                                                    

                                                  

                                                  

                                                    

                                                      
                                                      
                                                    

                                                  

                                                  

                                                    
                                                      
                                                      Download Plot
                                                    
                                                  

                                                

                                                

                                                
You can manually adjust the width and height to resize the plot as needed.

                                              

                                              

                                            

                                          

                                        

                                      

                                      
                                    

                                  

                                

                                
                              

                            

                          

                        

                        

                          

                            

                              

                                

                                  

                                    
Parameter

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      
                                    

                                    

                                    
Input hex codes or color names separated by comma. If filled, 'Palette' will be ignored.

                                    

                                      
                                      
                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      

                                        
                                        

                                          
                                          
                                        

                                      

                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      
                                    

                                  

                                

                                
                              

                            

                            

                              

                                

                                  

                                    
Plot and Data

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      

                                        

                                          
                                        

                                        

                                          

                                            

                                              

                                                

                                                  

                                                    

                                                      
                                                      
                                                    

                                                  

                                                  

                                                    

                                                      
                                                      
                                                    

                                                  

                                                  

                                                    
                                                      
                                                      Download Plot
                                                    
                                                  

                                                

                                                

                                                
You can manually adjust the width and height to resize the plot as needed.

                                              

                                              

                                            

                                          

                                        

                                      

                                      
                                    

                                  

                                

                                
                              

                            

                          

                        

                      

                    

                  

                  

                    

                    

                      
                      

                        

                          

                            

                              

                                

                                  

                                    
Parameter

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      
                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      

                                        
                                      

                                      

                                        
                                      

                                    

                                    

                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                  

                                

                                
                              

                              

                                

                                  

                                    
Data Download

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    
                                  

                                

                                
                              

                            

                            

                              

                                

                                  

                                    
Plot and Data

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      

                                        

                                          
                                        

                                        

                                          

                                            

                                              
                                              

                                            

                                          

                                        

                                      

                                      
                                    

                                  

                                

                                
                              

                            

                          

                        

                        

                          

                            

                              

                                

                                  

                                    
Parameter

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                  

                                

                                
                              

                              

                                

                                  

                                    
Data Download

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    
                                  

                                

                                
                              

                            

                            

                              

                                

                                  

                                    
Plot and Data

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      

                                        

                                          
                                        

                                        

                                          

                                            

                                              
                                              

                                            

                                          

                                        

                                      

                                      
                                    

                                  

                                

                                
                              

                            

                          

                        

                        

                          

                            

                              

                                

                                  

                                    
Parameter

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      
                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                    
Input hex codes or color names separated by comma. If you have group like subtype.

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                  

                                

                                
                              

                            

                            

                              

                                

                                  

                                    
Plot and Data

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      

                                        

                                          
                                        

                                        

                                          

                                            

                                              

                                                

                                                  

                                                    

                                                      
                                                      
                                                    

                                                  

                                                  

                                                    

                                                      
                                                      
                                                    

                                                  

                                                  

                                                    
                                                      
                                                      Download Plot
                                                    
                                                  

                                                

                                                

                                                
You can manually adjust the width and height to resize the plot as needed.

                                              

                                              

                                            

                                          

                                        

                                      

                                      
                                    

                                  

                                

                                
                              

                            

                          

                        

                        

                          

                            

                              

                                

                                  

                                    
Parameter

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      
                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      
                                    

                                    

                                    
Provide 2 or 3 colors separated by comma. 2 colors = low/high (mid=white); 3 colors = low/mid/high.

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                  

                                

                                
                              

                            

                            

                              

                                

                                  

                                    
Plot and Data

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      

                                        

                                          
                                        

                                        

                                          

                                            

                                              

                                                

                                                  

                                                    

                                                      
                                                      
                                                    

                                                  

                                                  

                                                    

                                                      
                                                      
                                                    

                                                  

                                                  

                                                    
                                                      
                                                      Download Plot
                                                    
                                                  

                                                

                                                

                                                
You can manually adjust the width and height to resize the plot as needed.

                                              

                                              

                                            

                                          

                                        

                                      

                                      
                                    

                                  

                                

                                
                              

                            

                          

                        

                      

                    

                  

                

              

            

            

              

                
Signature-Gene Workflow
      :
      Explore relationships between specific signatures and genes.

                

                  
                

              

              

                
                

                  

                    

                    

                      
                      

                        

                          

                            

                              
                              

                                

                                  

                                    
                                  

                                  

                                    
                                  

                                

                              

                            

                            Note: Select Counts to TPM or Annotate ExpressionSet.
                          

                          

                            

                              

                                

                                  

                                    

                                      
Parameter

                                      

                                        
                                        
                                      

                                    

                                    

                                      

                                        

                                          
                                          

                                            
                                            
                                          

                                          

                                            

                                          

                                        

                                        

                                          
                                        

                                      

                                      

                                        
                                      

                                      

                                        
                                        

                                          
                                          
                                        

                                      

                                      

                                        

                                          
                                          

                                            
                                            
                                          

                                        

                                      

                                      

                                        

                                          
                                          

                                            
                                            
                                          

                                        

                                      

                                      

                                        
                                        

                                          
                                          
                                        

                                      

                                      

                                        
                                        

                                          
                                          
                                        

                                      

                                    

                                  

                                  
                                

                                

                                  

                                    

                                      
Data Download

                                      

                                        
                                        
                                      

                                    

                                    

                                      

                                        
                                        

                                          
                                          
                                        

                                      

                                      
                                    

                                  

                                  
                                

                              

                              

                                

                                  

                                    

                                      
Plot and Data

                                      

                                        
                                        
                                      

                                    

                                    

                                      

                                        

                                          

                                            
                                          

                                          

                                            

                                              

                                                
                                                

                                              

                                            

                                          

                                        

                                        
                                      

                                    

                                  

                                  
                                

                              

                            

                          

                          

                            

                              

                                

                                  

                                    

                                      
Parameter

                                      

                                        
                                        
                                      

                                    

                                    

                                      

                                        

                                          
                                          

                                            
                                            
                                          

                                          

                                            

                                          

                                        

                                        

                                          
                                        

                                      

                                      

                                        
                                      

                                      

                                        
                                        

                                          
                                          
                                        

                                      

                                      

                                        
                                        

                                          
                                          
                                        

                                      

                                      

                                        
                                        

                                          
                                          
                                        

                                      

                                    

                                  

                                  
                                

                                

                                  

                                    

                                      
Data Download

                                      

                                        
                                        
                                      

                                    

                                    

                                      

                                        
                                        

                                          
                                          
                                        

                                      

                                      
                                    

                                  

                                  
                                

                              

                              

                                

                                  

                                    

                                      
Plot and Data

                                      

                                        
                                        
                                      

                                    

                                    

                                      

                                        

                                          

                                            
                                          

                                          

                                            

                                              

                                                
                                                

                                              

                                            

                                          

                                        

                                        
                                      

                                    

                                  

                                  
                                

                              

                            

                          

                        

                        

                          

                            

                              

                                

                                  

                                    
Parameter

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      
                                    

                                  

                                

                                
                              

                              

                                

                                  

                                    
Data Download

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    
                                  

                                

                                
                              

                            

                            

                              

                                

                                  

                                    
Plot and Data

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      

                                        

                                          
                                        

                                        

                                          

                                            

                                              
                                              

                                            

                                            

                                              

                                                

                                                  

                                                    

                                                      
                                                      
                                                    

                                                  

                                                  

                                                    

                                                      
                                                      
                                                    

                                                  

                                                  

                                                    
                                                      
                                                      Download Plot
                                                    
                                                  

                                                

                                                

                                                
You can manually adjust the width and height to resize the plot as needed.

                                              

                                              

                                            

                                            

                                              Identified Outlier Samples:
                                              

                                            

                                          

                                        

                                      

                                      
                                    

                                  

                                

                                
                              

                            

                          

                        

                        

                          

                            

                              

                                

                                  

                                    
Parameter

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      
                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                  

                                

                                
                              

                              

                                

                                  

                                    
Data Download

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    
                                  

                                

                                
                              

                            

                            

                              

                                

                                  

                                    
Plot and Data

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      

                                        

                                          
                                        

                                        

                                          

                                            

                                              
                                              

                                            

                                          

                                        

                                      

                                      
                                    

                                  

                                

                                
                              

                            

                          

                        

                      

                    

                  

                  

                    

                    

                      
                      

                        

                          

                            

                              

                                

                                  

                                    
Parameter

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      
                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      

                                        
                                      

                                      

                                        
                                      

                                    

                                    

                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                  

                                

                                
                              

                              

                                

                                  

                                    
Data Download

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    
                                  

                                

                                
                              

                            

                            

                              

                                

                                  

                                    
Plot and Data

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      

                                        

                                          
                                        

                                        

                                          

                                            

                                              
                                              

                                            

                                          

                                        

                                      

                                      
                                    

                                  

                                

                                
                              

                            

                          

                        

                        

                          

                            

                              

                                

                                  

                                    
Parameter

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      
                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                    
Input hex codes or color names separated by comma. If you have group like subtype.

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                  

                                

                                
                              

                            

                            

                              

                                

                                  

                                    
Plot and Data

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      

                                        

                                          
                                        

                                        

                                          

                                            

                                              

                                                

                                                  

                                                    

                                                      
                                                      
                                                    

                                                  

                                                  

                                                    

                                                      
                                                      
                                                    

                                                  

                                                  

                                                    
                                                      
                                                      Download Plot
                                                    
                                                  

                                                

                                                

                                                
You can manually adjust the width and height to resize the plot as needed.

                                              

                                              

                                            

                                          

                                        

                                      

                                      
                                    

                                  

                                

                                
                              

                            

                          

                        

                        

                          

                            

                              

                                

                                  

                                    
Parameter

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      
                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      
                                    

                                    

                                    
Provide 2 or 3 colors separated by comma. 2 colors = low/high (mid=white); 3 colors = low/mid/high.

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                  

                                

                                
                              

                            

                            

                              

                                

                                  

                                    
Plot and Data

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      

                                        

                                          
                                        

                                        

                                          

                                            

                                              

                                                

                                                  

                                                    

                                                      
                                                      
                                                    

                                                  

                                                  

                                                    

                                                      
                                                      
                                                    

                                                  

                                                  

                                                    
                                                      
                                                      Download Plot
                                                    
                                                  

                                                

                                                

                                                
You can manually adjust the width and height to resize the plot as needed.

                                              

                                              

                                            

                                          

                                        

                                      

                                      
                                    

                                  

                                

                                
                              

                            

                          

                        

                      

                    

                  

                

              

            

            

              
              
              

                
IOBRportal Database Statistics

                
        The IOBRportal integrates multi-omics data from four major cohorts: 
        TCGA Cohort, MOLC (Molecular Cohort) (predominantly GEO), IMMC (Immunotherapy Cohort), and 
        CLIC (Clinical Cohort) (including CPTAC and TARGET). 
        The data is structured into two primary analysis modes—Calculate Sigscore 
        and Deconvolute TME features—designed to facilitate comprehensive 
        downstream bioinformatics analyses.
      
              

              

              

                

                  

                    

                      
Database Overview

                      

                        
                      

                    

                    

                      

                    

                  

                  
                

                

                  

                    

                      
Cancer Types Distribution

                      

                        
                      

                    

                    

                      

                    

                  

                  
                

              

              

                

                  

                    

                      
Detailed Cohort Metadata

                      

                        
                      

                    

                    

                      

                    

                  

                  
                

                

                  

                    

                      
Quick Analysis Access

                      

                        
                      

                    

                    

                      

                      

                      
Select a cohort to start your analysis workflow immediately:

                      

                        

                          
                        

                        

                          
                        

                        

                          
                        

                        

                          
                        

                      

                    

                  

                  
                

              

            

            

              

                

                  

                    

                      

                        
Choose Data Source

                        

                          
                          
                        

                      

                      

                        

                          
                          

                            
                            
                          

                        

                      

                    

                    
                  

                  

                    

                      

                        
Method Parameters

                        

                          
                          
                        

                      

                      

                        

                          
                          

                            
                            
                          

                        

                        

                          

                            
                            

                              
                              
                            

                          

                          

                            

                              
                              

                                
                                
                              

                            

                          

                          

                            

                              
                              

                                
                                
                              

                            

                          

                        

                        

                          

                            
                            

                              
                              
                            

                          

                        

                      

                    

                    
                  

                  

                    
                  

                

                

                  

                    

                      

                        
Plot and Data

                        

                          
                          
                        

                      

                      

                        

                          

                            

                              
                            

                            

                              

                                

                                  
                                  

                                

                                

                                  
                                  

                                

                              

                            

                          

                          
                        

                      

                    

                    
                  

                

              

            

            

              

                

                  

                    

                      

                        
Choose Data Source

                        

                          
                          
                        

                      

                      

                        

                          
                          

                            
                            
                          

                        

                        

                          

                            
                            

                              
                              
                            

                          

                        

                        

                          

                            
                            

                              
                              
                            

                          

                        

                      

                    

                    
                  

                  

                    

                      

                        
Method Parameters

                        

                          
                          
                        

                      

                      

                        

                          
                          

                            
                            
                          

                        

                        

                          

                            
                            

                              
                              
                            

                          

                        

                        

                          

                            
                            

                              
                              
                            

                          

                        

                      

                    

                    
                  

                  

                    
                  

                

                

                  

                    

                      

                        
Plot and Data

                        

                          
                          
                        

                      

                      

                        

                          

                            

                              
                            

                            

                              

                                

                                  
                                  

                                

                                

                                  
                                  

                                

                              

                            

                          

                          
                        

                      

                    

                    
                  

                

              

            

            

              

                

                  

                    

                      

                        
Choose Data Source

                        

                          
                          
                        

                      

                      

                        

                          
                          
                        

                        

                          
                          
                        

                        

                          
                          
                        

                        

                          
                          
                        

                        

                          
                          
                        

                      

                    

                    
                  

                  

                    

                      

                        
Method Parameters

                        

                          
                          
                        

                      

                      

                        

                          
                          

                            
                            
                          

                        

                        

                          

                            
                            

                              
                              
                            

                          

                        

                        

                          

                            
                            

                              
                              
                            

                          

                        

                      

                    

                    
                  

                  

                    
                  

                

                

                  

                    

                      

                        
Plot and Data

                        

                          
                          
                        

                      

                      

                        

                          

                            

                              
                            

                            

                              

                                

                                  
                                  

                                

                              

                            

                          

                          
                        

                      

                    

                    
                  

                

              

            

            

              

                

                  

                    

                      

                        
Choose Data Source

                        

                          
                          
                        

                      

                      

                        

                          
                          
                        

                        

                          
                          
                        

                      

                    

                    
                  

                  

                    

                      

                        
Method Parameters

                        

                          
                          
                        

                      

                      

                        

                          
                          

                            
                            
                          

                        

                        

                          

                            
                            

                              
                              
                            

                          

                          

                            

                              
                              

                                
                                
                              

                            

                          

                          

                            

                              
                              

                                
                                
                              

                            

                          

                        

                        

                          

                            
                            

                              
                              
                            

                          

                        

                      

                    

                    
                  

                  

                    
                  

                

                

                  

                    

                      

                        
Plot and Data

                        

                          
                          
                        

                      

                      

                        

                          

                            

                              
                            

                            

                              

                                

                                  
                                  

                                

                              

                            

                          

                          
                        

                      

                    

                    
                  

                

              

            

            

              

                
TCGA Cohorts Workflow
      :
       Database-driven Pipeline for Signature Scoring, TME Deconvolution, and Downstream Analysis.

                

                  
                

              

              

                
                

                  

                    

                    

                      
                      

                        

                          

                            

                              

                                

                                  

                                    
Choose Data Source

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                  

                                

                                
                              

                              

                                

                                  

                                    
Method Parameters

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      

                                        
                                        

                                          
                                          
                                        

                                      

                                      

                                        

                                          
                                          

                                            
                                            
                                          

                                        

                                      

                                      

                                        

                                          
                                          

                                            
                                            
                                          

                                        

                                      

                                    

                                    

                                      

                                        
                                        

                                          
                                          
                                        

                                      

                                    

                                  

                                

                                
                              

                              

                                
                              

                            

                            

                              

                                

                                  

                                    
Plot and Data

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      

                                        

                                          
                                        

                                        

                                          

                                            

                                              
                                              

                                            

                                            

                                              
                                              

                                            

                                          

                                        

                                      

                                      
                                    

                                  

                                

                                
                              

                            

                          

                        

                        

                          

                            

                              

                                

                                  

                                    
Parameter

                                    

                                      
                                      
                                    

                                  

                                  

                                    
Optional: select interesting features for TME clustering; leave empty to skip this step.

                                    

                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                  

                                

                                
                              

                              

                                

                                  

                                    
Data Download

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    
                                  

                                

                                
                              

                            

                            

                              

                                

                                  

                                    
Plot and Data

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      

                                        

                                          
                                        

                                        

                                          

                                            

                                              
                                              

                                            

                                            

                                              

                                            

                                          

                                        

                                      

                                      
                                    

                                  

                                

                                
                              

                            

                          

                        

                      

                    

                  

                  

                    

                    

                      
                      

                        

                          

                            

                              

                                

                                  

                                    
Parameter

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      
                                    

                                    

                                    
Input hex codes or color names separated by comma. If filled, 'Palette Group' will be ignored.

                                    

                                      
                                      
                                    

                                    

                                    
Provide at least 3 colors separated by comma. Used for heatmap low-mid-high values.

                                    

                                      
                                      
                                    

                                  

                                

                                
                              

                            

                            

                              

                                

                                  

                                    
Plot

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      

                                        

                                          
                                        

                                        

                                          

                                            

                                              

                                                

                                                  

                                                    

                                                      
                                                      
                                                    

                                                  

                                                  

                                                    

                                                      
                                                      
                                                    

                                                  

                                                  

                                                    
                                                      
                                                      Download Plot
                                                    
                                                  

                                                

                                                

                                                
You can manually adjust the width and height to resize the plot as needed.

                                              

                                              

                                            

                                          

                                        

                                      

                                      
                                    

                                  

                                

                                
                              

                            

                          

                        

                        

                          

                            

                              

                                

                                  

                                    
Parameter

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      
                                    

                                    

                                    
Input hex codes or color names separated by comma. If filled, 'Palette' will be ignored.

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                  

                                

                                
                              

                            

                            

                              

                                

                                  

                                    
Plot and Data

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      

                                        

                                          
                                        

                                        

                                          

                                            

                                              

                                                

                                                  

                                                    

                                                      
                                                      
                                                    

                                                  

                                                  

                                                    

                                                      
                                                      
                                                    

                                                  

                                                  

                                                    
                                                      
                                                      Download Plot
                                                    
                                                  

                                                

                                                

                                                
You can manually adjust the width and height to resize the plot as needed.

                                              

                                              

                                            

                                          

                                        

                                      

                                      
                                    

                                  

                                

                                
                              

                            

                          

                        

                        

                          

                            

                              

                                

                                  

                                    
Parameter

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      
                                    

                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      
                                    

                                    

                                    
Input hex codes or color names separated by comma. If filled, 'Palette' will be ignored.

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                  

                                

                                
                              

                            

                            

                              

                                

                                  

                                    
Plot and Data

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      

                                        

                                          
                                        

                                        

                                          

                                            

                                              

                                                

                                                  

                                                    

                                                      
                                                      
                                                    

                                                  

                                                  

                                                    

                                                      
                                                      
                                                    

                                                  

                                                  

                                                    
                                                      
                                                      Download Plot
                                                    
                                                  

                                                

                                                

                                                
You can manually adjust the width and height to resize the plot as needed.

                                              

                                              

                                            

                                          

                                        

                                      

                                      
                                    

                                  

                                

                                
                              

                            

                          

                        

                        

                          

                            

                              

                                

                                  

                                    
Parameter

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      
                                    

                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                    
Note: Supports data from deconvolution methods such as CIBERSORT, EPIC, and quanTIseq.

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                    
Input hex codes or color names separated by comma.

                                    

                                      
                                      
                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                  

                                

                                
                              

                            

                            

                              

                                

                                  

                                    
Plot and Data

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      

                                        

                                          
                                        

                                        

                                          

                                            

                                              

                                                

                                                  

                                                    

                                                      
                                                      
                                                    

                                                  

                                                  

                                                    

                                                      
                                                      
                                                    

                                                  

                                                  

                                                    
                                                      
                                                      Download Plot
                                                    
                                                  

                                                

                                                

                                                
You can manually adjust the width and height to resize the plot as needed.

                                              

                                              

                                            

                                          

                                        

                                      

                                      
                                    

                                  

                                

                                
                              

                            

                          

                        

                      

                    

                  

                  

                    

                    

                      
                      

                        

                          

                            

                              

                                

                                  

                                    
Parameter

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                  

                                

                                
                              

                              

                                

                                  

                                    
Data Download

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    
                                  

                                

                                
                              

                            

                            

                              

                                

                                  

                                    
Plot and Data

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      

                                        

                                          
                                        

                                        

                                          

                                            

                                              
                                              

                                            

                                          

                                        

                                      

                                      
                                    

                                  

                                

                                
                              

                            

                          

                        

                        

                          

                            

                              

                                

                                  

                                    
Parameter

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                  

                                

                                
                              

                              

                                

                                  

                                    
Data Download

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    
                                  

                                

                                
                              

                            

                            

                              

                                

                                  

                                    
Plot and Data

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      

                                        

                                          
                                        

                                        

                                          

                                            

                                              
                                              

                                            

                                          

                                        

                                      

                                      
                                    

                                  

                                

                                
                              

                            

                          

                        

                        

                          

                            

                              

                                

                                  

                                    
Parameter

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                    
The signatures will be auto-selected

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      
                                    

                                    

                                    
Input hex codes or color names separated by comma. If filled, 'Palette Group' will be ignored.

                                    

                                      
                                      
                                    

                                    

                                    
Provide at least 3 colors separated by comma. Used for heatmap low-mid-high values.

                                    

                                      
                                      
                                    

                                  

                                

                                
                              

                            

                            

                              

                                

                                  

                                    
Plot

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      

                                        

                                          
                                        

                                        

                                          

                                            

                                              

                                                

                                                  

                                                    

                                                      
                                                      
                                                    

                                                  

                                                  

                                                    

                                                      
                                                      
                                                    

                                                  

                                                  

                                                    
                                                      
                                                      Download Plot
                                                    
                                                  

                                                

                                                

                                                
You can manually adjust the width and height to resize the plot as needed.

                                              

                                              

                                            

                                          

                                        

                                      

                                      
                                    

                                  

                                

                                
                              

                            

                          

                        

                        

                          

                            

                              

                                

                                  

                                    
Parameter

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      
                                    

                                    

                                    
Input hex codes or color names separated by comma. If filled, 'Palette' will be ignored.

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                  

                                

                                
                              

                            

                            

                              

                                

                                  

                                    
Plot and Data

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      

                                        

                                          
                                        

                                        

                                          

                                            

                                              

                                                

                                                  

                                                    

                                                      
                                                      
                                                    

                                                  

                                                  

                                                    

                                                      
                                                      
                                                    

                                                  

                                                  

                                                    
                                                      
                                                      Download Plot
                                                    
                                                  

                                                

                                                

                                                
You can manually adjust the width and height to resize the plot as needed.

                                              

                                              

                                            

                                          

                                        

                                      

                                      
                                    

                                  

                                

                                
                              

                            

                          

                        

                      

                    

                  

                  

                    

                    

                      
                      

                        

                          

                            

                              

                                

                                  

                                    
Parameter

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                  

                                

                                
                              

                              

                                

                                  

                                    
Data Download

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    
                                  

                                

                                
                              

                            

                            

                              

                                

                                  

                                    
Plot and Data

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      

                                        

                                          
                                        

                                        

                                          

                                            

                                              
                                              

                                            

                                          

                                        

                                      

                                      
                                    

                                  

                                

                                
                              

                            

                          

                        

                        

                          

                            

                              

                                

                                  

                                    
Parameter

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      
                                    

                                    

                                    
Note: Supports data from Signature Data rather than TME data.

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                    
Input hex codes or color names separated by comma. If filled, 'Palette' will be ignored.

                                  

                                

                                
                              

                            

                            

                              

                                

                                  

                                    
Plot and Data

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      

                                        

                                          
                                        

                                        

                                          

                                            

                                              

                                                

                                                  

                                                    

                                                      
                                                      
                                                    

                                                  

                                                  

                                                    

                                                      
                                                      
                                                    

                                                  

                                                  

                                                    
                                                      
                                                      Download Plot
                                                    
                                                  

                                                

                                                

                                                
You can manually adjust the width and height to resize the plot as needed.

                                              

                                              

                                            

                                          

                                        

                                      

                                      
                                    

                                  

                                

                                
                              

                            

                          

                        

                        

                          

                            

                              

                                

                                  

                                    
Parameter

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                    
The signatures will be auto-selected

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      
                                    

                                    

                                    
Input hex codes or color names separated by comma. If filled, 'Palette Group' will be ignored.

                                    

                                      
                                      
                                    

                                    

                                    
Provide at least 3 colors separated by comma. Used for heatmap low-mid-high values.

                                    

                                      
                                      
                                    

                                  

                                

                                
                              

                            

                            

                              

                                

                                  

                                    
Plot

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      

                                        

                                          
                                        

                                        

                                          

                                            

                                              

                                                

                                                  

                                                    

                                                      
                                                      
                                                    

                                                  

                                                  

                                                    

                                                      
                                                      
                                                    

                                                  

                                                  

                                                    
                                                      
                                                      Download Plot
                                                    
                                                  

                                                

                                                

                                                
You can manually adjust the width and height to resize the plot as needed.

                                              

                                              

                                            

                                          

                                        

                                      

                                      
                                    

                                  

                                

                                
                              

                            

                          

                        

                        

                          

                            

                              

                                

                                  

                                    
Parameter

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      
                                    

                                    

                                    
Input hex codes or color names separated by comma. If filled, 'Palette' will be ignored.

                                  

                                

                                
                              

                            

                            

                              

                                

                                  

                                    
Plot and Data

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      

                                        

                                          
                                        

                                        

                                          

                                            

                                              

                                                

                                                  

                                                    

                                                      
                                                      
                                                    

                                                  

                                                  

                                                    

                                                      
                                                      
                                                    

                                                  

                                                  

                                                    
                                                      
                                                      Download Plot
                                                    
                                                  

                                                

                                                

                                                
You can manually adjust the width and height to resize the plot as needed.

                                              

                                              

                                            

                                          

                                        

                                      

                                      
                                    

                                  

                                

                                
                              

                            

                          

                        

                        

                          

                            

                              

                                

                                  

                                    
Parameter

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      
                                    

                                    

                                    
Input hex codes or color names separated by comma. If filled, 'Palette' will be ignored.

                                    

                                      
                                      
                                    

                                  

                                

                                
                              

                            

                            

                              

                                

                                  

                                    
Plot and Data

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      

                                        

                                          
                                        

                                        

                                          

                                            

                                              

                                                

                                                  

                                                    

                                                      
                                                      
                                                    

                                                  

                                                  

                                                    

                                                      
                                                      
                                                    

                                                  

                                                  

                                                    
                                                      
                                                      Download Plot
                                                    
                                                  

                                                

                                                

                                                
You can manually adjust the width and height to resize the plot as needed.

                                              

                                              

                                            

                                          

                                        

                                      

                                      
                                    

                                  

                                

                                
                              

                            

                          

                        

                        

                          

                            

                              

                                

                                  

                                    
Parameter

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      
                                    

                                    

                                    
Input hex codes or color names separated by comma. If filled, 'Palette' will be ignored.

                                    

                                      
                                      
                                    

                                  

                                

                                
                              

                            

                            

                              

                                

                                  

                                    
Plot and Data

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      

                                        

                                          
                                        

                                        

                                          

                                            

                                              

                                                

                                                  

                                                    

                                                      
                                                      
                                                    

                                                  

                                                  

                                                    

                                                      
                                                      
                                                    

                                                  

                                                  

                                                    
                                                      
                                                      Download Plot
                                                    
                                                  

                                                

                                                

                                                
You can manually adjust the width and height to resize the plot as needed.

                                              

                                              

                                            

                                          

                                        

                                      

                                      
                                    

                                  

                                

                                
                              

                            

                          

                        

                        

                          

                            

                              

                                

                                  

                                    
Parameter

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      
                                    

                                    

                                    
Input hex codes or color names separated by comma. If filled, 'Palette' will be ignored.

                                    

                                      
                                      
                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      

                                        
                                        

                                          
                                          
                                        

                                      

                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      
                                    

                                  

                                

                                
                              

                            

                            

                              

                                

                                  

                                    
Plot and Data

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      

                                        

                                          
                                        

                                        

                                          

                                            

                                              

                                                

                                                  

                                                    

                                                      
                                                      
                                                    

                                                  

                                                  

                                                    

                                                      
                                                      
                                                    

                                                  

                                                  

                                                    
                                                      
                                                      Download Plot
                                                    
                                                  

                                                

                                                

                                                
You can manually adjust the width and height to resize the plot as needed.

                                              

                                              

                                            

                                          

                                        

                                      

                                      
                                    

                                  

                                

                                
                              

                            

                          

                        

                      

                    

                  

                  

                    

                    

                      
                      

                        

                          

                            

                              

                                

                                  

                                    
Parameter

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      
                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      

                                        
                                      

                                      

                                        
                                      

                                    

                                    

                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                  

                                

                                
                              

                              

                                

                                  

                                    
Data Download

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    
                                  

                                

                                
                              

                            

                            

                              

                                

                                  

                                    
Plot and Data

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      

                                        

                                          
                                        

                                        

                                          

                                            

                                              
                                              

                                            

                                          

                                        

                                      

                                      
                                    

                                  

                                

                                
                              

                            

                          

                        

                        

                          

                            

                              

                                

                                  

                                    
Parameter

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                  

                                

                                
                              

                              

                                

                                  

                                    
Data Download

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    
                                  

                                

                                
                              

                            

                            

                              

                                

                                  

                                    
Plot and Data

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      

                                        

                                          
                                        

                                        

                                          

                                            

                                              
                                              

                                            

                                          

                                        

                                      

                                      
                                    

                                  

                                

                                
                              

                            

                          

                        

                        

                          

                            

                              

                                

                                  

                                    
Parameter

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      
                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                    
Input hex codes or color names separated by comma. If you have group like subtype.

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                  

                                

                                
                              

                            

                            

                              

                                

                                  

                                    
Plot and Data

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      

                                        

                                          
                                        

                                        

                                          

                                            

                                              

                                                

                                                  

                                                    

                                                      
                                                      
                                                    

                                                  

                                                  

                                                    

                                                      
                                                      
                                                    

                                                  

                                                  

                                                    
                                                      
                                                      Download Plot
                                                    
                                                  

                                                

                                                

                                                
You can manually adjust the width and height to resize the plot as needed.

                                              

                                              

                                            

                                          

                                        

                                      

                                      
                                    

                                  

                                

                                
                              

                            

                          

                        

                        

                          

                            

                              

                                

                                  

                                    
Parameter

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      
                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      
                                    

                                    

                                    
Provide 2 or 3 colors separated by comma. 2 colors = low/high (mid=white); 3 colors = low/mid/high.

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                  

                                

                                
                              

                            

                            

                              

                                

                                  

                                    
Plot and Data

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      

                                        

                                          
                                        

                                        

                                          

                                            

                                              

                                                

                                                  

                                                    

                                                      
                                                      
                                                    

                                                  

                                                  

                                                    

                                                      
                                                      
                                                    

                                                  

                                                  

                                                    
                                                      
                                                      Download Plot
                                                    
                                                  

                                                

                                                

                                                
You can manually adjust the width and height to resize the plot as needed.

                                              

                                              

                                            

                                          

                                        

                                      

                                      
                                    

                                  

                                

                                
                              

                            

                          

                        

                      

                    

                  

                

              

            

            

              

                
TCGA Mutation Workflow
      :
       Database-driven Mutation–Signature and Survival Analysis.

                

                  
                

              

              

                
                

                  

                    

                      

                        

                          

                            

                              
Choose Data Source

                              

                                
                                
                              

                            

                            

                              

                                
                                

                                  
                                  
                                

                              

                              

                                
                                

                                  
                                  
                                

                              

                            

                          

                          
                        

                        

                          

                            

                              
Signature Data

                              

                                
                                
                              

                            

                            

                              

                                
                                

                                  
                                  
                                

                              

                              

                                

                                  
                                  

                                    
                                    
                                  

                                

                              

                              

                                

                                  
                                  

                                    
                                    
                                  

                                

                              

                            

                          

                          
                        

                        

                          
                        

                      

                      

                        

                          

                            

                              
Prepared Data

                              

                                
                                
                              

                            

                            

                              

                                

                                  

                                    
                                  

                                  

                                    

                                      

                                        
                                        

                                      

                                      

                                        
                                        

                                      

                                      

                                        
                                        

                                      

                                    

                                  

                                

                                
                              

                            

                          

                          
                        

                      

                    

                  

                  

                    

                      

                        

                          

                            

                              
Parameter

                              

                                
                                
                              

                            

                            

                              

                                
                              

                              

                                
                                
                              

                              

                                
                                
                              

                              

                                
                                

                                  
                                  
                                

                              

                              

                                
                                

                                  
                                  
                                

                              

                            

                          

                          
                        

                        

                          

                            

                              
Parameter for oncoprint

                              

                                
                                
                              

                            

                            

                              

                                
                                

                                  
                                  
                                

                              

                              

                                
                                
                              

                              
Input a hex code or color name for mutation events.

                              

                                
                                
                              

                            

                          

                          
                        

                        

                          

                            

                              
Parameter for box plot

                              

                                
                                
                              

                            

                            

                              

                                
                                
                              

                              

                                
                                
                              

                              

                                
                                

                                  
                                  
                                

                              

                              

                                
                                
                              

                              

                              
Input hex codes or color names separated by comma. If filled, 'Palette' will be ignored.

                              

                                
                                

                                  
                                  
                                

                              

                            

                          

                          
                        

                        

                          

                            

                              
All Results Download

                              

                                
                                
                              

                            

                            

                              

                                
                                
                              

                              
                            

                          

                          
                        

                      

                      

                        

                          

                            

                              
Plot and Data

                              

                                
                                
                              

                            

                            

                              

                                

                                  

                                    
                                  

                                  

                                    

                                      

                                        

                                          

                                            

                                              

                                                
                                                
                                              

                                            

                                            

                                              

                                                
                                                
                                              

                                            

                                            

                                              
                                                
                                                Download Plot
                                              
                                            

                                          

                                          

                                          
You can manually adjust the width and height to resize the plot as needed.

                                        

                                        

                                      

                                      

                                        

                                          

                                            

                                              

                                                
                                                
                                              

                                            

                                            

                                              

                                                
                                                
                                              

                                            

                                            

                                              
                                                
                                                Download Plot
                                              
                                            

                                          

                                          

                                          
You can manually adjust the width and height to resize the plot as needed.

                                        

                                        

                                      

                                    

                                  

                                

                                
                              

                            

                          

                          
                        

                      

                    

                  

                  

                    

                      
                      

                        

                          

                            

                              

                                

                                  

                                    
Parameter

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                  

                                

                                
                              

                              

                                

                                  

                                    
Data Download

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    
                                  

                                

                                
                              

                            

                            

                              

                                

                                  

                                    
Plot and Data

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      

                                        

                                          
                                        

                                        

                                          

                                            

                                              
                                              

                                            

                                          

                                        

                                      

                                      
                                    

                                  

                                

                                
                              

                            

                          

                        

                        

                          

                            

                              

                                

                                  

                                    
Parameter

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      
                                    

                                    

                                    
Input hex codes or color names separated by comma. If filled, 'Palette' will be ignored.

                                    

                                      
                                      
                                    

                                  

                                

                                
                              

                            

                            

                              

                                

                                  

                                    
Plot and Data

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      

                                        

                                          
                                        

                                        

                                          

                                            

                                              

                                                

                                                  

                                                    

                                                      
                                                      
                                                    

                                                  

                                                  

                                                    

                                                      
                                                      
                                                    

                                                  

                                                  

                                                    
                                                      
                                                      Download Plot
                                                    
                                                  

                                                

                                                

                                                
You can manually adjust the width and height to resize the plot as needed.

                                              

                                              

                                            

                                          

                                        

                                      

                                      
                                    

                                  

                                

                                
                              

                            

                          

                        

                      

                    

                  

                

              

            

            

              

                
CLIC Workflow
      :
       Database-driven Pipeline for Signature Scoring, TME Deconvolution, and Downstream Analysis.

                

                  
                

              

              

                
                

                  

                    

                    

                      
                      

                        

                          

                            

                              

                                

                                  

                                    
Choose Data Source

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      

                                        
                                        

                                          
                                          
                                        

                                      

                                    

                                    

                                      

                                        
                                        

                                          
                                          
                                        

                                      

                                    

                                  

                                

                                
                              

                              

                                

                                  

                                    
Method Parameters

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      

                                        
                                        

                                          
                                          
                                        

                                      

                                    

                                    

                                      

                                        
                                        

                                          
                                          
                                        

                                      

                                    

                                  

                                

                                
                              

                              

                                
                              

                            

                            

                              

                                

                                  

                                    
Plot and Data

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      

                                        

                                          
                                        

                                        

                                          

                                            

                                              
                                              

                                            

                                            

                                              
                                              

                                            

                                          

                                        

                                      

                                      
                                    

                                  

                                

                                
                              

                            

                          

                        

                        

                          

                            

                              

                                

                                  

                                    
Parameter

                                    

                                      
                                      
                                    

                                  

                                  

                                    
Optional: select interesting features for TME clustering; leave empty to skip this step.

                                    

                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                  

                                

                                
                              

                              

                                

                                  

                                    
Data Download

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    
                                  

                                

                                
                              

                            

                            

                              

                                

                                  

                                    
Plot and Data

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      

                                        

                                          
                                        

                                        

                                          

                                            

                                              
                                              

                                            

                                            

                                              

                                            

                                          

                                        

                                      

                                      
                                    

                                  

                                

                                
                              

                            

                          

                        

                      

                    

                  

                  

                    

                    

                      
                      

                        

                          

                            

                              

                                

                                  

                                    
Parameter

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      
                                    

                                    

                                    
Input hex codes or color names separated by comma. If filled, 'Palette Group' will be ignored.

                                    

                                      
                                      
                                    

                                    

                                    
Provide at least 3 colors separated by comma. Used for heatmap low-mid-high values.

                                    

                                      
                                      
                                    

                                  

                                

                                
                              

                            

                            

                              

                                

                                  

                                    
Plot

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      

                                        

                                          
                                        

                                        

                                          

                                            

                                              

                                                

                                                  

                                                    

                                                      
                                                      
                                                    

                                                  

                                                  

                                                    

                                                      
                                                      
                                                    

                                                  

                                                  

                                                    
                                                      
                                                      Download Plot
                                                    
                                                  

                                                

                                                

                                                
You can manually adjust the width and height to resize the plot as needed.

                                              

                                              

                                            

                                          

                                        

                                      

                                      
                                    

                                  

                                

                                
                              

                            

                          

                        

                        

                          

                            

                              

                                

                                  

                                    
Parameter

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      
                                    

                                    

                                    
Input hex codes or color names separated by comma. If filled, 'Palette' will be ignored.

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                  

                                

                                
                              

                            

                            

                              

                                

                                  

                                    
Plot and Data

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      

                                        

                                          
                                        

                                        

                                          

                                            

                                              

                                                

                                                  

                                                    

                                                      
                                                      
                                                    

                                                  

                                                  

                                                    

                                                      
                                                      
                                                    

                                                  

                                                  

                                                    
                                                      
                                                      Download Plot
                                                    
                                                  

                                                

                                                

                                                
You can manually adjust the width and height to resize the plot as needed.

                                              

                                              

                                            

                                          

                                        

                                      

                                      
                                    

                                  

                                

                                
                              

                            

                          

                        

                        

                          

                            

                              

                                

                                  

                                    
Parameter

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      
                                    

                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      
                                    

                                    

                                    
Input hex codes or color names separated by comma. If filled, 'Palette' will be ignored.

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                  

                                

                                
                              

                            

                            

                              

                                

                                  

                                    
Plot and Data

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      

                                        

                                          
                                        

                                        

                                          

                                            

                                              

                                                

                                                  

                                                    

                                                      
                                                      
                                                    

                                                  

                                                  

                                                    

                                                      
                                                      
                                                    

                                                  

                                                  

                                                    
                                                      
                                                      Download Plot
                                                    
                                                  

                                                

                                                

                                                
You can manually adjust the width and height to resize the plot as needed.

                                              

                                              

                                            

                                          

                                        

                                      

                                      
                                    

                                  

                                

                                
                              

                            

                          

                        

                        

                          

                            

                              

                                

                                  

                                    
Parameter

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      
                                    

                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                    
Note: Supports data from deconvolution methods such as CIBERSORT, EPIC, and quanTIseq.

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                    
Input hex codes or color names separated by comma.

                                    

                                      
                                      
                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                  

                                

                                
                              

                            

                            

                              

                                

                                  

                                    
Plot and Data

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      

                                        

                                          
                                        

                                        

                                          

                                            

                                              

                                                

                                                  

                                                    

                                                      
                                                      
                                                    

                                                  

                                                  

                                                    

                                                      
                                                      
                                                    

                                                  

                                                  

                                                    
                                                      
                                                      Download Plot
                                                    
                                                  

                                                

                                                

                                                
You can manually adjust the width and height to resize the plot as needed.

                                              

                                              

                                            

                                          

                                        

                                      

                                      
                                    

                                  

                                

                                
                              

                            

                          

                        

                      

                    

                  

                  

                    

                    

                      
                      

                        

                          

                            

                              

                                

                                  

                                    
Parameter

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                  

                                

                                
                              

                              

                                

                                  

                                    
Data Download

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    
                                  

                                

                                
                              

                            

                            

                              

                                

                                  

                                    
Plot and Data

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      

                                        

                                          
                                        

                                        

                                          

                                            

                                              
                                              

                                            

                                          

                                        

                                      

                                      
                                    

                                  

                                

                                
                              

                            

                          

                        

                        

                          

                            

                              

                                

                                  

                                    
Parameter

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                  

                                

                                
                              

                              

                                

                                  

                                    
Data Download

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    
                                  

                                

                                
                              

                            

                            

                              

                                

                                  

                                    
Plot and Data

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      

                                        

                                          
                                        

                                        

                                          

                                            

                                              
                                              

                                            

                                          

                                        

                                      

                                      
                                    

                                  

                                

                                
                              

                            

                          

                        

                        

                          

                            

                              

                                

                                  

                                    
Parameter

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                    
The signatures will be auto-selected

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      
                                    

                                    

                                    
Input hex codes or color names separated by comma. If filled, 'Palette Group' will be ignored.

                                    

                                      
                                      
                                    

                                    

                                    
Provide at least 3 colors separated by comma. Used for heatmap low-mid-high values.

                                    

                                      
                                      
                                    

                                  

                                

                                
                              

                            

                            

                              

                                

                                  

                                    
Plot

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      

                                        

                                          
                                        

                                        

                                          

                                            

                                              

                                                

                                                  

                                                    

                                                      
                                                      
                                                    

                                                  

                                                  

                                                    

                                                      
                                                      
                                                    

                                                  

                                                  

                                                    
                                                      
                                                      Download Plot
                                                    
                                                  

                                                

                                                

                                                
You can manually adjust the width and height to resize the plot as needed.

                                              

                                              

                                            

                                          

                                        

                                      

                                      
                                    

                                  

                                

                                
                              

                            

                          

                        

                        

                          

                            

                              

                                

                                  

                                    
Parameter

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      
                                    

                                    

                                    
Input hex codes or color names separated by comma. If filled, 'Palette' will be ignored.

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                  

                                

                                
                              

                            

                            

                              

                                

                                  

                                    
Plot and Data

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      

                                        

                                          
                                        

                                        

                                          

                                            

                                              

                                                

                                                  

                                                    

                                                      
                                                      
                                                    

                                                  

                                                  

                                                    

                                                      
                                                      
                                                    

                                                  

                                                  

                                                    
                                                      
                                                      Download Plot
                                                    
                                                  

                                                

                                                

                                                
You can manually adjust the width and height to resize the plot as needed.

                                              

                                              

                                            

                                          

                                        

                                      

                                      
                                    

                                  

                                

                                
                              

                            

                          

                        

                      

                    

                  

                  

                    

                    

                      
                      

                        

                          

                            

                              

                                

                                  

                                    
Parameter

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                  

                                

                                
                              

                              

                                

                                  

                                    
Data Download

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    
                                  

                                

                                
                              

                            

                            

                              

                                

                                  

                                    
Plot and Data

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      

                                        

                                          
                                        

                                        

                                          

                                            

                                              
                                              

                                            

                                          

                                        

                                      

                                      
                                    

                                  

                                

                                
                              

                            

                          

                        

                        

                          

                            

                              

                                

                                  

                                    
Parameter

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      
                                    

                                    

                                    
Note: Supports data from Signature Data rather than TME data.

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                    
Input hex codes or color names separated by comma. If filled, 'Palette' will be ignored.

                                  

                                

                                
                              

                            

                            

                              

                                

                                  

                                    
Plot and Data

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      

                                        

                                          
                                        

                                        

                                          

                                            

                                              

                                                

                                                  

                                                    

                                                      
                                                      
                                                    

                                                  

                                                  

                                                    

                                                      
                                                      
                                                    

                                                  

                                                  

                                                    
                                                      
                                                      Download Plot
                                                    
                                                  

                                                

                                                

                                                
You can manually adjust the width and height to resize the plot as needed.

                                              

                                              

                                            

                                          

                                        

                                      

                                      
                                    

                                  

                                

                                
                              

                            

                          

                        

                        

                          

                            

                              

                                

                                  

                                    
Parameter

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                    
The signatures will be auto-selected

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      
                                    

                                    

                                    
Input hex codes or color names separated by comma. If filled, 'Palette Group' will be ignored.

                                    

                                      
                                      
                                    

                                    

                                    
Provide at least 3 colors separated by comma. Used for heatmap low-mid-high values.

                                    

                                      
                                      
                                    

                                  

                                

                                
                              

                            

                            

                              

                                

                                  

                                    
Plot

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      

                                        

                                          
                                        

                                        

                                          

                                            

                                              

                                                

                                                  

                                                    

                                                      
                                                      
                                                    

                                                  

                                                  

                                                    

                                                      
                                                      
                                                    

                                                  

                                                  

                                                    
                                                      
                                                      Download Plot
                                                    
                                                  

                                                

                                                

                                                
You can manually adjust the width and height to resize the plot as needed.

                                              

                                              

                                            

                                          

                                        

                                      

                                      
                                    

                                  

                                

                                
                              

                            

                          

                        

                        

                          

                            

                              

                                

                                  

                                    
Parameter

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      
                                    

                                    

                                    
Input hex codes or color names separated by comma. If filled, 'Palette' will be ignored.

                                  

                                

                                
                              

                            

                            

                              

                                

                                  

                                    
Plot and Data

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      

                                        

                                          
                                        

                                        

                                          

                                            

                                              

                                                

                                                  

                                                    

                                                      
                                                      
                                                    

                                                  

                                                  

                                                    

                                                      
                                                      
                                                    

                                                  

                                                  

                                                    
                                                      
                                                      Download Plot
                                                    
                                                  

                                                

                                                

                                                
You can manually adjust the width and height to resize the plot as needed.

                                              

                                              

                                            

                                          

                                        

                                      

                                      
                                    

                                  

                                

                                
                              

                            

                          

                        

                        

                          

                            

                              

                                

                                  

                                    
Parameter

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      
                                    

                                    

                                    
Input hex codes or color names separated by comma. If filled, 'Palette' will be ignored.

                                    

                                      
                                      
                                    

                                  

                                

                                
                              

                            

                            

                              

                                

                                  

                                    
Plot and Data

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      

                                        

                                          
                                        

                                        

                                          

                                            

                                              

                                                

                                                  

                                                    

                                                      
                                                      
                                                    

                                                  

                                                  

                                                    

                                                      
                                                      
                                                    

                                                  

                                                  

                                                    
                                                      
                                                      Download Plot
                                                    
                                                  

                                                

                                                

                                                
You can manually adjust the width and height to resize the plot as needed.

                                              

                                              

                                            

                                          

                                        

                                      

                                      
                                    

                                  

                                

                                
                              

                            

                          

                        

                        

                          

                            

                              

                                

                                  

                                    
Parameter

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      
                                    

                                    

                                    
Input hex codes or color names separated by comma. If filled, 'Palette' will be ignored.

                                    

                                      
                                      
                                    

                                  

                                

                                
                              

                            

                            

                              

                                

                                  

                                    
Plot and Data

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      

                                        

                                          
                                        

                                        

                                          

                                            

                                              

                                                

                                                  

                                                    

                                                      
                                                      
                                                    

                                                  

                                                  

                                                    

                                                      
                                                      
                                                    

                                                  

                                                  

                                                    
                                                      
                                                      Download Plot
                                                    
                                                  

                                                

                                                

                                                
You can manually adjust the width and height to resize the plot as needed.

                                              

                                              

                                            

                                          

                                        

                                      

                                      
                                    

                                  

                                

                                
                              

                            

                          

                        

                        

                          

                            

                              

                                

                                  

                                    
Parameter

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      
                                    

                                    

                                    
Input hex codes or color names separated by comma. If filled, 'Palette' will be ignored.

                                    

                                      
                                      
                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      

                                        
                                        

                                          
                                          
                                        

                                      

                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      
                                    

                                  

                                

                                
                              

                            

                            

                              

                                

                                  

                                    
Plot and Data

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      

                                        

                                          
                                        

                                        

                                          

                                            

                                              

                                                

                                                  

                                                    

                                                      
                                                      
                                                    

                                                  

                                                  

                                                    

                                                      
                                                      
                                                    

                                                  

                                                  

                                                    
                                                      
                                                      Download Plot
                                                    
                                                  

                                                

                                                

                                                
You can manually adjust the width and height to resize the plot as needed.

                                              

                                              

                                            

                                          

                                        

                                      

                                      
                                    

                                  

                                

                                
                              

                            

                          

                        

                      

                    

                  

                  

                    

                    

                      
                      

                        

                          

                            

                              

                                

                                  

                                    
Parameter

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      
                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      

                                        
                                      

                                      

                                        
                                      

                                    

                                    

                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                  

                                

                                
                              

                              

                                

                                  

                                    
Data Download

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    
                                  

                                

                                
                              

                            

                            

                              

                                

                                  

                                    
Plot and Data

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      

                                        

                                          
                                        

                                        

                                          

                                            

                                              
                                              

                                            

                                          

                                        

                                      

                                      
                                    

                                  

                                

                                
                              

                            

                          

                        

                        

                          

                            

                              

                                

                                  

                                    
Parameter

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                  

                                

                                
                              

                              

                                

                                  

                                    
Data Download

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    
                                  

                                

                                
                              

                            

                            

                              

                                

                                  

                                    
Plot and Data

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      

                                        

                                          
                                        

                                        

                                          

                                            

                                              
                                              

                                            

                                          

                                        

                                      

                                      
                                    

                                  

                                

                                
                              

                            

                          

                        

                        

                          

                            

                              

                                

                                  

                                    
Parameter

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      
                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                    
Input hex codes or color names separated by comma. If you have group like subtype.

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                  

                                

                                
                              

                            

                            

                              

                                

                                  

                                    
Plot and Data

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      

                                        

                                          
                                        

                                        

                                          

                                            

                                              

                                                

                                                  

                                                    

                                                      
                                                      
                                                    

                                                  

                                                  

                                                    

                                                      
                                                      
                                                    

                                                  

                                                  

                                                    
                                                      
                                                      Download Plot
                                                    
                                                  

                                                

                                                

                                                
You can manually adjust the width and height to resize the plot as needed.

                                              

                                              

                                            

                                          

                                        

                                      

                                      
                                    

                                  

                                

                                
                              

                            

                          

                        

                        

                          

                            

                              

                                

                                  

                                    
Parameter

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      
                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      
                                    

                                    

                                    
Provide 2 or 3 colors separated by comma. 2 colors = low/high (mid=white); 3 colors = low/mid/high.

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                  

                                

                                
                              

                            

                            

                              

                                

                                  

                                    
Plot and Data

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      

                                        

                                          
                                        

                                        

                                          

                                            

                                              

                                                

                                                  

                                                    

                                                      
                                                      
                                                    

                                                  

                                                  

                                                    

                                                      
                                                      
                                                    

                                                  

                                                  

                                                    
                                                      
                                                      Download Plot
                                                    
                                                  

                                                

                                                

                                                
You can manually adjust the width and height to resize the plot as needed.

                                              

                                              

                                            

                                          

                                        

                                      

                                      
                                    

                                  

                                

                                
                              

                            

                          

                        

                      

                    

                  

                

              

            

            

              

                
IMMC Workflow
      :
       Database-driven Pipeline for Signature Scoring, TME Deconvolution, and Some Downstream Analysis.

                

                  
                

              

              

                
                

                  

                    

                    

                      
                      

                        

                          

                            

                              

                                

                                  

                                    
Choose Data Source

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                  

                                

                                
                              

                              

                                

                                  

                                    
Method Parameters

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      

                                        
                                        

                                          
                                          
                                        

                                      

                                    

                                    

                                      

                                        
                                        

                                          
                                          
                                        

                                      

                                    

                                  

                                

                                
                              

                              

                                
                              

                            

                            

                              

                                

                                  

                                    
Plot and Data

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      

                                        

                                          
                                        

                                        

                                          

                                            

                                              
                                              

                                            

                                          

                                        

                                      

                                      
                                    

                                  

                                

                                
                              

                            

                          

                        

                        

                          

                            

                              

                                

                                  

                                    
Parameter

                                    

                                      
                                      
                                    

                                  

                                  

                                    
Optional: select interesting features for TME clustering; leave empty to skip this step.

                                    

                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                  

                                

                                
                              

                              

                                

                                  

                                    
Data Download

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    
                                  

                                

                                
                              

                            

                            

                              

                                

                                  

                                    
Plot and Data

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      

                                        

                                          
                                        

                                        

                                          

                                            

                                              
                                              

                                            

                                            

                                              

                                            

                                          

                                        

                                      

                                      
                                    

                                  

                                

                                
                              

                            

                          

                        

                      

                    

                  

                  

                    

                    

                      
                      

                        

                          

                            

                              

                                

                                  

                                    
Parameter

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      
                                    

                                    

                                    
Input hex codes or color names separated by comma. If filled, 'Palette Group' will be ignored.

                                    

                                      
                                      
                                    

                                    

                                    
Provide at least 3 colors separated by comma. Used for heatmap low-mid-high values.

                                    

                                      
                                      
                                    

                                  

                                

                                
                              

                            

                            

                              

                                

                                  

                                    
Plot

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      

                                        

                                          
                                        

                                        

                                          

                                            

                                              

                                                

                                                  

                                                    

                                                      
                                                      
                                                    

                                                  

                                                  

                                                    

                                                      
                                                      
                                                    

                                                  

                                                  

                                                    
                                                      
                                                      Download Plot
                                                    
                                                  

                                                

                                                

                                                
You can manually adjust the width and height to resize the plot as needed.

                                              

                                              

                                            

                                          

                                        

                                      

                                      
                                    

                                  

                                

                                
                              

                            

                          

                        

                        

                          

                            

                              

                                

                                  

                                    
Parameter

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      
                                    

                                    

                                    
Input hex codes or color names separated by comma. If filled, 'Palette' will be ignored.

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                  

                                

                                
                              

                            

                            

                              

                                

                                  

                                    
Plot and Data

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      

                                        

                                          
                                        

                                        

                                          

                                            

                                              

                                                

                                                  

                                                    

                                                      
                                                      
                                                    

                                                  

                                                  

                                                    

                                                      
                                                      
                                                    

                                                  

                                                  

                                                    
                                                      
                                                      Download Plot
                                                    
                                                  

                                                

                                                

                                                
You can manually adjust the width and height to resize the plot as needed.

                                              

                                              

                                            

                                          

                                        

                                      

                                      
                                    

                                  

                                

                                
                              

                            

                          

                        

                        

                          

                            

                              

                                

                                  

                                    
Parameter

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      
                                    

                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                    
Note: Supports data from deconvolution methods such as CIBERSORT, EPIC, and quanTIseq.

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                    
Input hex codes or color names separated by comma.

                                    

                                      
                                      
                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                  

                                

                                
                              

                            

                            

                              

                                

                                  

                                    
Plot and Data

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      

                                        

                                          
                                        

                                        

                                          

                                            

                                              

                                                

                                                  

                                                    

                                                      
                                                      
                                                    

                                                  

                                                  

                                                    

                                                      
                                                      
                                                    

                                                  

                                                  

                                                    
                                                      
                                                      Download Plot
                                                    
                                                  

                                                

                                                

                                                
You can manually adjust the width and height to resize the plot as needed.

                                              

                                              

                                            

                                          

                                        

                                      

                                      
                                    

                                  

                                

                                
                              

                            

                          

                        

                      

                    

                  

                  

                    

                    

                      
                      

                        

                          

                            

                              

                                

                                  

                                    
Parameter

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                  

                                

                                
                              

                              

                                

                                  

                                    
Data Download

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    
                                  

                                

                                
                              

                            

                            

                              

                                

                                  

                                    
Plot and Data

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      

                                        

                                          
                                        

                                        

                                          

                                            

                                              
                                              

                                            

                                          

                                        

                                      

                                      
                                    

                                  

                                

                                
                              

                            

                          

                        

                        

                          

                            

                              

                                

                                  

                                    
Parameter

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                  

                                

                                
                              

                              

                                

                                  

                                    
Data Download

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    
                                  

                                

                                
                              

                            

                            

                              

                                

                                  

                                    
Plot and Data

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      

                                        

                                          
                                        

                                        

                                          

                                            

                                              
                                              

                                            

                                          

                                        

                                      

                                      
                                    

                                  

                                

                                
                              

                            

                          

                        

                        

                          

                            

                              

                                

                                  

                                    
Parameter

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                    
The signatures will be auto-selected

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      
                                    

                                    

                                    
Input hex codes or color names separated by comma. If filled, 'Palette Group' will be ignored.

                                    

                                      
                                      
                                    

                                    

                                    
Provide at least 3 colors separated by comma. Used for heatmap low-mid-high values.

                                    

                                      
                                      
                                    

                                  

                                

                                
                              

                            

                            

                              

                                

                                  

                                    
Plot

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      

                                        

                                          
                                        

                                        

                                          

                                            

                                              

                                                

                                                  

                                                    

                                                      
                                                      
                                                    

                                                  

                                                  

                                                    

                                                      
                                                      
                                                    

                                                  

                                                  

                                                    
                                                      
                                                      Download Plot
                                                    
                                                  

                                                

                                                

                                                
You can manually adjust the width and height to resize the plot as needed.

                                              

                                              

                                            

                                          

                                        

                                      

                                      
                                    

                                  

                                

                                
                              

                            

                          

                        

                        

                          

                            

                              

                                

                                  

                                    
Parameter

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      
                                    

                                    

                                    
Input hex codes or color names separated by comma. If filled, 'Palette' will be ignored.

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                  

                                

                                
                              

                            

                            

                              

                                

                                  

                                    
Plot and Data

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      

                                        

                                          
                                        

                                        

                                          

                                            

                                              

                                                

                                                  

                                                    

                                                      
                                                      
                                                    

                                                  

                                                  

                                                    

                                                      
                                                      
                                                    

                                                  

                                                  

                                                    
                                                      
                                                      Download Plot
                                                    
                                                  

                                                

                                                

                                                
You can manually adjust the width and height to resize the plot as needed.

                                              

                                              

                                            

                                          

                                        

                                      

                                      
                                    

                                  

                                

                                
                              

                            

                          

                        

                      

                    

                  

                  

                    

                    

                      
                      

                        

                          

                            

                              

                                

                                  

                                    
Parameter

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      
                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      

                                        
                                      

                                      

                                        
                                      

                                    

                                    

                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                  

                                

                                
                              

                              

                                

                                  

                                    
Data Download

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    
                                  

                                

                                
                              

                            

                            

                              

                                

                                  

                                    
Plot and Data

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      

                                        

                                          
                                        

                                        

                                          

                                            

                                              
                                              

                                            

                                          

                                        

                                      

                                      
                                    

                                  

                                

                                
                              

                            

                          

                        

                        

                          

                            

                              

                                

                                  

                                    
Parameter

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                  

                                

                                
                              

                              

                                

                                  

                                    
Data Download

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    
                                  

                                

                                
                              

                            

                            

                              

                                

                                  

                                    
Plot and Data

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      

                                        

                                          
                                        

                                        

                                          

                                            

                                              
                                              

                                            

                                          

                                        

                                      

                                      
                                    

                                  

                                

                                
                              

                            

                          

                        

                        

                          

                            

                              

                                

                                  

                                    
Parameter

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      
                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                    
Input hex codes or color names separated by comma. If you have group like subtype.

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                  

                                

                                
                              

                            

                            

                              

                                

                                  

                                    
Plot and Data

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      

                                        

                                          
                                        

                                        

                                          

                                            

                                              

                                                

                                                  

                                                    

                                                      
                                                      
                                                    

                                                  

                                                  

                                                    

                                                      
                                                      
                                                    

                                                  

                                                  

                                                    
                                                      
                                                      Download Plot
                                                    
                                                  

                                                

                                                

                                                
You can manually adjust the width and height to resize the plot as needed.

                                              

                                              

                                            

                                          

                                        

                                      

                                      
                                    

                                  

                                

                                
                              

                            

                          

                        

                        

                          

                            

                              

                                

                                  

                                    
Parameter

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      
                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      
                                    

                                    

                                    
Provide 2 or 3 colors separated by comma. 2 colors = low/high (mid=white); 3 colors = low/mid/high.

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                  

                                

                                
                              

                            

                            

                              

                                

                                  

                                    
Plot and Data

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      

                                        

                                          
                                        

                                        

                                          

                                            

                                              

                                                

                                                  

                                                    

                                                      
                                                      
                                                    

                                                  

                                                  

                                                    

                                                      
                                                      
                                                    

                                                  

                                                  

                                                    
                                                      
                                                      Download Plot
                                                    
                                                  

                                                

                                                

                                                
You can manually adjust the width and height to resize the plot as needed.

                                              

                                              

                                            

                                          

                                        

                                      

                                      
                                    

                                  

                                

                                
                              

                            

                          

                        

                      

                    

                  

                

              

            

            

              

                
MOLC Workflow
      :
       Database-driven Pipeline for Signature Scoring, TME Deconvolution, and Some Downstream Analysis.

                

                  
                

              

              

                
                

                  

                    

                    

                      
                      

                        

                          

                            

                              

                                

                                  

                                    
Choose Data Source

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                  

                                

                                
                              

                              

                                

                                  

                                    
Method Parameters

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      

                                        
                                        

                                          
                                          
                                        

                                      

                                      

                                        

                                          
                                          

                                            
                                            
                                          

                                        

                                      

                                      

                                        

                                          
                                          

                                            
                                            
                                          

                                        

                                      

                                    

                                    

                                      

                                        
                                        

                                          
                                          
                                        

                                      

                                    

                                  

                                

                                
                              

                              

                                
                              

                            

                            

                              

                                

                                  

                                    
Plot and Data

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      

                                        

                                          
                                        

                                        

                                          

                                            

                                              
                                              

                                            

                                          

                                        

                                      

                                      
                                    

                                  

                                

                                
                              

                            

                          

                        

                        

                          

                            

                              

                                

                                  

                                    
Parameter

                                    

                                      
                                      
                                    

                                  

                                  

                                    
Optional: select interesting features for TME clustering; leave empty to skip this step.

                                    

                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                  

                                

                                
                              

                              

                                

                                  

                                    
Data Download

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    
                                  

                                

                                
                              

                            

                            

                              

                                

                                  

                                    
Plot and Data

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      

                                        

                                          
                                        

                                        

                                          

                                            

                                              
                                              

                                            

                                            

                                              

                                            

                                          

                                        

                                      

                                      
                                    

                                  

                                

                                
                              

                            

                          

                        

                      

                    

                  

                  

                    

                    

                      
                      

                        

                          

                            

                              

                                

                                  

                                    
Parameter

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      
                                    

                                    

                                    
Input hex codes or color names separated by comma. If filled, 'Palette Group' will be ignored.

                                    

                                      
                                      
                                    

                                    

                                    
Provide at least 3 colors separated by comma. Used for heatmap low-mid-high values.

                                    

                                      
                                      
                                    

                                  

                                

                                
                              

                            

                            

                              

                                

                                  

                                    
Plot

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      

                                        

                                          
                                        

                                        

                                          

                                            

                                              

                                                

                                                  

                                                    

                                                      
                                                      
                                                    

                                                  

                                                  

                                                    

                                                      
                                                      
                                                    

                                                  

                                                  

                                                    
                                                      
                                                      Download Plot
                                                    
                                                  

                                                

                                                

                                                
You can manually adjust the width and height to resize the plot as needed.

                                              

                                              

                                            

                                          

                                        

                                      

                                      
                                    

                                  

                                

                                
                              

                            

                          

                        

                        

                          

                            

                              

                                

                                  

                                    
Parameter

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      
                                    

                                    

                                    
Input hex codes or color names separated by comma. If filled, 'Palette' will be ignored.

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                  

                                

                                
                              

                            

                            

                              

                                

                                  

                                    
Plot and Data

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      

                                        

                                          
                                        

                                        

                                          

                                            

                                              

                                                

                                                  

                                                    

                                                      
                                                      
                                                    

                                                  

                                                  

                                                    

                                                      
                                                      
                                                    

                                                  

                                                  

                                                    
                                                      
                                                      Download Plot
                                                    
                                                  

                                                

                                                

                                                
You can manually adjust the width and height to resize the plot as needed.

                                              

                                              

                                            

                                          

                                        

                                      

                                      
                                    

                                  

                                

                                
                              

                            

                          

                        

                        

                          

                            

                              

                                

                                  

                                    
Parameter

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      
                                    

                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                    
Note: Supports data from deconvolution methods such as CIBERSORT, EPIC, and quanTIseq.

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                    
Input hex codes or color names separated by comma.

                                    

                                      
                                      
                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                  

                                

                                
                              

                            

                            

                              

                                

                                  

                                    
Plot and Data

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      

                                        

                                          
                                        

                                        

                                          

                                            

                                              

                                                

                                                  

                                                    

                                                      
                                                      
                                                    

                                                  

                                                  

                                                    

                                                      
                                                      
                                                    

                                                  

                                                  

                                                    
                                                      
                                                      Download Plot
                                                    
                                                  

                                                

                                                

                                                
You can manually adjust the width and height to resize the plot as needed.

                                              

                                              

                                            

                                          

                                        

                                      

                                      
                                    

                                  

                                

                                
                              

                            

                          

                        

                      

                    

                  

                  

                    

                    

                      
                      

                        

                          

                            

                              

                                

                                  

                                    
Parameter

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                  

                                

                                
                              

                              

                                

                                  

                                    
Data Download

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    
                                  

                                

                                
                              

                            

                            

                              

                                

                                  

                                    
Plot and Data

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      

                                        

                                          
                                        

                                        

                                          

                                            

                                              
                                              

                                            

                                          

                                        

                                      

                                      
                                    

                                  

                                

                                
                              

                            

                          

                        

                        

                          

                            

                              

                                

                                  

                                    
Parameter

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                  

                                

                                
                              

                              

                                

                                  

                                    
Data Download

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    
                                  

                                

                                
                              

                            

                            

                              

                                

                                  

                                    
Plot and Data

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      

                                        

                                          
                                        

                                        

                                          

                                            

                                              
                                              

                                            

                                          

                                        

                                      

                                      
                                    

                                  

                                

                                
                              

                            

                          

                        

                        

                          

                            

                              

                                

                                  

                                    
Parameter

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                    
The signatures will be auto-selected

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      
                                    

                                    

                                    
Input hex codes or color names separated by comma. If filled, 'Palette Group' will be ignored.

                                    

                                      
                                      
                                    

                                    

                                    
Provide at least 3 colors separated by comma. Used for heatmap low-mid-high values.

                                    

                                      
                                      
                                    

                                  

                                

                                
                              

                            

                            

                              

                                

                                  

                                    
Plot

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      

                                        

                                          
                                        

                                        

                                          

                                            

                                              

                                                

                                                  

                                                    

                                                      
                                                      
                                                    

                                                  

                                                  

                                                    

                                                      
                                                      
                                                    

                                                  

                                                  

                                                    
                                                      
                                                      Download Plot
                                                    
                                                  

                                                

                                                

                                                
You can manually adjust the width and height to resize the plot as needed.

                                              

                                              

                                            

                                          

                                        

                                      

                                      
                                    

                                  

                                

                                
                              

                            

                          

                        

                        

                          

                            

                              

                                

                                  

                                    
Parameter

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      
                                    

                                    

                                    
Input hex codes or color names separated by comma. If filled, 'Palette' will be ignored.

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                  

                                

                                
                              

                            

                            

                              

                                

                                  

                                    
Plot and Data

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      

                                        

                                          
                                        

                                        

                                          

                                            

                                              

                                                

                                                  

                                                    

                                                      
                                                      
                                                    

                                                  

                                                  

                                                    

                                                      
                                                      
                                                    

                                                  

                                                  

                                                    
                                                      
                                                      Download Plot
                                                    
                                                  

                                                

                                                

                                                
You can manually adjust the width and height to resize the plot as needed.

                                              

                                              

                                            

                                          

                                        

                                      

                                      
                                    

                                  

                                

                                
                              

                            

                          

                        

                      

                    

                  

                  

                    

                    

                      
                      

                        

                          

                            

                              

                                

                                  

                                    
Parameter

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      
                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      

                                        
                                      

                                      

                                        
                                      

                                    

                                    

                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                  

                                

                                
                              

                              

                                

                                  

                                    
Data Download

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    
                                  

                                

                                
                              

                            

                            

                              

                                

                                  

                                    
Plot and Data

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      

                                        

                                          
                                        

                                        

                                          

                                            

                                              
                                              

                                            

                                          

                                        

                                      

                                      
                                    

                                  

                                

                                
                              

                            

                          

                        

                        

                          

                            

                              

                                

                                  

                                    
Parameter

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                  

                                

                                
                              

                              

                                

                                  

                                    
Data Download

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    
                                  

                                

                                
                              

                            

                            

                              

                                

                                  

                                    
Plot and Data

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      

                                        

                                          
                                        

                                        

                                          

                                            

                                              
                                              

                                            

                                          

                                        

                                      

                                      
                                    

                                  

                                

                                
                              

                            

                          

                        

                        

                          

                            

                              

                                

                                  

                                    
Parameter

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      
                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                    
Input hex codes or color names separated by comma. If you have group like subtype.

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                  

                                

                                
                              

                            

                            

                              

                                

                                  

                                    
Plot and Data

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      

                                        

                                          
                                        

                                        

                                          

                                            

                                              

                                                

                                                  

                                                    

                                                      
                                                      
                                                    

                                                  

                                                  

                                                    

                                                      
                                                      
                                                    

                                                  

                                                  

                                                    
                                                      
                                                      Download Plot
                                                    
                                                  

                                                

                                                

                                                
You can manually adjust the width and height to resize the plot as needed.

                                              

                                              

                                            

                                          

                                        

                                      

                                      
                                    

                                  

                                

                                
                              

                            

                          

                        

                        

                          

                            

                              

                                

                                  

                                    
Parameter

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      
                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      
                                    

                                    

                                    
Provide 2 or 3 colors separated by comma. 2 colors = low/high (mid=white); 3 colors = low/mid/high.

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      
                                    

                                    

                                      
                                      

                                        
                                        
                                      

                                    

                                  

                                

                                
                              

                            

                            

                              

                                

                                  

                                    
Plot and Data

                                    

                                      
                                      
                                    

                                  

                                  

                                    

                                      

                                        

                                          
                                        

                                        

                                          

                                            

                                              

                                                

                                                  

                                                    

                                                      
                                                      
                                                    

                                                  

                                                  

                                                    

                                                      
                                                      
                                                    

                                                  

                                                  

                                                    
                                                      
                                                      Download Plot
                                                    
                                                  

                                                

                                                

                                                
You can manually adjust the width and height to resize the plot as needed.